Skip to main content

Biochemical diagnosis of occupational exposure to lead toxicity

This is a preview of subscription content, access via your institution.

References

  1. Beritic T, Pripic-Majic D, Karacic V, Telisman S (1977) ALA.D/EP ratio as a measure of lead toxicity. J Occup Med 19:551–557

    PubMed  Google Scholar 

  2. Bortoli A, Fazzin G, Marin U, Trabuio G, Zotti S (1986) Relationship between blood lead concentration and aminolevulinic acid dehydratase in alcoholics and workers industrially exposed to lead. Arch Environ Health 41(4):251–260.

    PubMed  Google Scholar 

  3. Chisolm J J Jr (1974) Disturbances in the Biosynthesis of heme in lead intoxication. J Pediatr 64:174–187.

    Google Scholar 

  4. Clausen J, Rastogi SC (1977) Heavy metal pollution among autoworkers. 1. Lead. Br J Ind Med 34:208–215

    PubMed  Google Scholar 

  5. Cramer K (1966) pre-disposing factors for lead poisoning. Acta Med Scand 179 (Suppl. 445):56

    Google Scholar 

  6. David N R, Curtis E C, John M, Fertig A (1982) Screening for lead toxicity among autobody repair workers. Am J Ind Med 3:405–412

    PubMed  Google Scholar 

  7. Giri S K, Shields C K, Little John D, Ottaway J L (1983) Determination of lead in whole blood by electrothermal atomic absorption spectrophotometry using graphite probe atomisation. Analyst 108:244–252

    PubMed  Google Scholar 

  8. Grandjean P (1979) Occupational lead exposure in Denmark: Screening with hematofluorometer. BR J Ind Med 36:52–58

    PubMed  Google Scholar 

  9. Grandjean P, Fischbein A (1980) Diseases associated with exposure to metals. In: Last J M (ed) “Public health and preventive medicine”. Appleton — Century Crafts, New York, pp 648–655

    Google Scholar 

  10. Granick J L, Sassa S, Granick S, Levere R D, Kappas A (1973) Studies in lead poisoning. II Correlation between the ratio of activated to inactivated Aminolevulinicacid dehydratase of whole blood level. Biochem Med 8:149–159

    PubMed  Google Scholar 

  11. Guerin M R, Rubin I B, Rao T K, Clark B R, Epler J L (1981) Distribution of mutagenic activity in petroleum and petroleum substitutes. Fuel 60:282–288

    Google Scholar 

  12. Heller J R, Labbe R F, Nutter J (1971) A Simplified assay for porphyrins in whole blood. Clin Chem 17:525–528

    PubMed  Google Scholar 

  13. Lamola A A, Yamane T (1974) Zinc protoporphyrins in the erythrocytes of patients with lead poisoning and iron deficiency anemia. Science 186:936–938

    PubMed  Google Scholar 

  14. Lilis R, Valciukas J A, Singer R, Glickman L, Kon S, Sarkozi L, Campbell C, Selikoff I J (1981) Assessment of lead health hazards in an autobody shop of an automobile assembly plant. Report to national institute of environmental health sciences, June 1, U.S.A. 1981

  15. Ludwig J H, Diggs D R, Hesselberg H E, Maga J A (1965) Survey of lead in the atmosphere of three urban communities a summary. Amer Ind Hyg Assoc J 26:270–284

    Google Scholar 

  16. Millar J A, Baltistein V, Cumming R L C, Carswell F, Goldberg A (1970) lead and δ-aminolevulinic acid dehydratase levels in mentally retarded children and in lead poisoned suckling rats. Lancet 11:695–698

    Google Scholar 

  17. Quinn M J (1985) Factors affecting blood lead concentrations in the UK. Results of the EEC blood lead surveys 1979-81. Int J Epid 14:420–431

    Google Scholar 

  18. Raghavan S R V, Dwight — Culver B, Gonick H C (1980) Erythrocyte lead binding protein after occupational exposure. Environ Research 22:264–269

    Google Scholar 

  19. Sassa S, Granick S, Kappas A (1975) Effect of lead and genetic factors on heme biosynthesis in human red cell. Ann N Y Acad Sci 244:419–440

    PubMed  Google Scholar 

  20. Sassa S (1978) Toxic effects of lead with particular reference to porphyrin and heme metabolism. In: De matties F, Aldridge WN (eds) Hand Book of experimental pharmacology, Vol. 44, Springer-Verlag, Berlin, p 333

    Google Scholar 

  21. Shemin D (1975) Structure and function of δ-aminolevulinic acid dehydratase. “Porphyrins in human diseases”, 1st International porphyrin meeting, Freiberg, Germany, p 15

    Google Scholar 

  22. Tomokuni K, Ogata M (1976) Relationship between lead concentration in blood and biological response for porphyrin metabolism in workers occupationally exposed to lead. Arch Toxicol 35:239–246

    PubMed  Google Scholar 

  23. World Health Organization (1977) Environmental Health Criteria. 3. Lead. WHO: Geneva

    Google Scholar 

Download references

Author information

Affiliations

Authors

Corresponding author

Correspondence to A. R. K. Prasad.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Somashekaraiah, B.V., Venkaiah, B. & Prasad, A.R.K. Biochemical diagnosis of occupational exposure to lead toxicity. Bull. Environ. Contam. Toxicol. 44, 268–275 (1990). https://doi.org/10.1007/BF01700146

Download citation

Keywords

  • Toxicity
  • Waste Water
  • Water Management
  • Water Pollution
  • Occupational Exposure