Summary
Seven patients with acute promyelocytic leukemia (APL) were treated with all-trans retinoic acid (ATRA). Five (71.4%) achieved complete remission (CR). Most side effects were transient and well tolerated. Hyperleukocytosis was the major adverse effect. These observations confirm the efficacy of ATRA for inducing CR in APL.
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Hernández, P., Carnot, J., Dorticós, E. et al. All-trans retinoic acid in acute promyelocytic leukemia: Preliminary results in Cuba. Ann Hematol 65, 121–123 (1992). https://doi.org/10.1007/BF01695810
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DOI: https://doi.org/10.1007/BF01695810