The use of hydroxyapatite in orthopaedic surgery: A ten-year review

Summary

Hydroxyapatite (HA), which constitutes 65% of the mineral component of human bone, is a crystalline structure whose synthesis was achieved at the beginning of the century. The development of the technology of coating metals with a ceramic material stimulated extensive research throughout the world leading to the use of implants coated with HA in maxillofacial surgery. The application to ostearticular implants was preceded by rigorous and prolonged experimentation, which demonstrated that implants of titanium coated with HA were devoid of risk and made it possible to secure excellent bony fixation. With a follow-up well in excess of 10 years the published results are evidence of considerable improvement and confirm that articular implants coated with HA represent a major advance. However, HA is only involved in bony fixation and cannot compensate for inadequate design of the implants as regards their shape or surface state.

This is a preview of subscription content, access via your institution.

References

  1. 1.

    Bonel G, Tourenne F, Rouquet N, Frayssinet P (1994) Couches minces d'hydroxyapatite. Caractéristiques et techniques d'application. In: Hydroxyapatite et prothèses articulaires, vol. 50. L'expansion Scientifique, Paris, pp 20–25

    Google Scholar 

  2. 2.

    Doyle C (1994) Hydroxyapatite: les facteurs “P”. In: Hydroxyapatite et prothèses articulaires, vol. 50. L'expansion Scientifique, Paris, pp 26–28

    Google Scholar 

  3. 3.

    De Groot K (1983) Ceramics of calcium phosphate: preparation and properties. In: K. Degroot, Bioceramics of calcium phosphate, pp 102–110, CRC Press, Boca Raton, Florida

    Google Scholar 

  4. 4.

    Epinette JA, Geesink RGT (1995) Hydroxyapatite coated hip and knee arthroplasty, vol. 51. L'expansion Scientifique, Paris, et (1994) Hydroxyapatite et prothèses articulaires, vol. 50. L'expansion Scientifique, Paris

    Google Scholar 

  5. 5.

    Furlong RJ (1987) The Furlong Hydroxyapatite Ceramic Coated Total Hip Replacement. London (England), Joint Replacement Instrumentation Ltd 16 pp

  6. 6.

    Geesink RGT, de Groot K, Klein CPAT (1987) Chemical implant fixation using hydroxylapatite coatings. Clin. Orthop. 225, 147–170

    PubMed  Google Scholar 

  7. 7.

    Jaffe WL, Scott DF (1996) Total hip arthroplasty with hydroxyapatite-coated prostheses, J. Bone Joint Surg. 78-A, 1918–1934

    Google Scholar 

  8. 8.

    Klein CPAT, Driessen A, de Groot K (1984) Relationship between the degradation behavior of calcium phosphate ceramics and their physical-chemical characteristics and ultrastructural geometry. Biomaterials, 5, 157–160

    PubMed  Google Scholar 

  9. 9.

    Oonishi H, Yamamoto M, Ishimaru H, Tsuji E, Kushitani S, Aono M, Ukon Y (1989) The effect of hydroxyapatite coating on bone growth into porous coated titanium alloys implants. J. Bone Joint Surg. 71-B, 213–216.

    Google Scholar 

  10. 10.

    Manley MT, Edidin AA (1995) Calcium phosphate biomaterials. In: Hydroxyapatite coated hip and knee arthroplasty, vol. 51. L'expansion Scientifique, Paris, pp 5–9

    Google Scholar 

  11. 11.

    Søballe K, Hansen ES, Rasmussen HB, Bünger C (1994) Etudes expérimentales des revêtements d'hydroxyapatite. In: Hydroxyapatite et prothèses articulaires, vol. 50. L'expansion Scientifique, Paris, pp, 61–81

    Google Scholar 

  12. 12.

    Thomas KA, Cook SD, Kay JF, Jarcho M, Anderson RC, Harding AF, Reynolds MC (1986) Attachment strength and histology of HA coated implants. In Saha S: Biomedical engineering V. Recent developments. Proceedings of the Fifth Southern Biomedical Engineering Conference, New York, NY, Pergamon Press, 205–211

    Google Scholar 

Download references

Author information

Affiliations

Authors

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Petit, R. The use of hydroxyapatite in orthopaedic surgery: A ten-year review. Eur J Orthop Surg Traumatol 9, 71–74 (1999). https://doi.org/10.1007/BF01695730

Download citation

Key word

  • Hydroxyapatite