References
Heger JJ, Prystowsky EN, Jackman WM, Naccarelli GV, Warfel KA, Rinkenberger RL, Zipes DP (1981) Amiodarone: clinical efficacy and electrophysiology during long term therapy for recurrent ventricular tachycardia and ventricular fibrillation. N Engl J Med 305:539–545
Canada AT, Lesko LJ, Haffajee CI, Johnson B, Asdouian GK (1983) Amiodarone for tachyarrhythmias: pharmacology, kinetics, and efficacy. Drug Intell Clin Pharm 17:100–104
Martin WJ II, Kachel DL, Vilen T, Natarajan V (1989) Mechanism of phospholipidosis in amiodarone pulmonary toxicity. J Pharmacol Exp Ther 251:272–278
Martin WJ II, Rosenow EC III (1988) Amiodarone pulmonary toxicity: I. Recognition and pathogenesis. Chest 93:1067–1075
Adams PC, Holt DW, Storey GCA, Morley AR, Callaghan J, Campbell WF (1985) Amiodarone and its desethyl metabolite; tissue distribution and morphologic changes during long-term therapy. Circulation 72:1064–1075
Wood DL, Osborn MJ, Rook J, Holmes DR (1985) Amiodarone pulmonary toxicity report of two cases associated with rapidly progressive fatal adult respiratory distress syndrome after pulmonary angiography. Mayo Clin Proc 60:601–603
Nalos PC, Kass RM, Gang ES, Fishbein MC, Mandel WJ, Peter T (1987) Life-threatening postoperative pulmonary complications in patients with previous amiodarone pulmonary toxicity undergoing cardiothoracic operations. J Thorac Cardiovasc Surg 93:904–912
Kudenchuk PJ, Pierson DJ, Greene HL, Graham EL, Sears GK, Trobaugh GB (1984) Perspective evaluation of amiodarone pulmonary toxicity. Chest 86:541–548
Martin WJ II (1990) Mechanisms of amiodarone pulmonary toxicity. Clin Chest Med 11:131–138
Camus P, Mendenhale HM (1986) Pulmonary sequestration of amiodarone and desethylamiodarone. J Pharmacol Exp Ther 237:867–873
Hostetler KY, Reasor MJ, Walker ER, Yazaki PJ, Frazee BW (1986) Role of phospholipase A inhibition in amiodarone pulmonary toxicity in rats. Biochim Biophys Acta 875:400–405
Martin WJ II, Standing JE (1988) Amiodarone pulmonary toxicity: biochemical evidence for a cellular phospolipidosis in the bronchoalveolar lavage of human subjects. J Pharmacol Exp Ther 244:774–779
Akoun GM, Gauthier-Rahman S, Milleron BJ, Perrot JY, Mayaud CM (1984) Amiodarone-induced hypersensitivity pneumonitis; evidence of an immunological cell-mediated mechanism. Chest 85:133–135
Akoun GM, Milleron BJ, Badaro DM, Mayaud CM, Liote HA (1989) Pleural T-lymphocyte subsets in amiodarone-associated plenuropneumonitis. Chest 95:596–597
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Supported in part by NIH grant HL36124
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Retz, J.L., Martin, W.J. Amiodarone pulmonary toxicity. Intensive Care Med 18, 388–390 (1992). https://doi.org/10.1007/BF01694339
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DOI: https://doi.org/10.1007/BF01694339