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Lack of evidence of nosocomial cross-infection byBurkholderia cepacia among danish cystic fibrosis patients

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Abstract

Burkholderia cepacia isolates from nine of the ten Danish cystic fibrosis (CF) patients known between 1975 and the present day to carry this organism were investigated. Eight distinct genotypes were found with polymerase chain reaction ribotyping and pulsed-field gel electrophoresis. The results indicate that there is little patient-to-patient cross-infection withBurkholderia cepacia within the Danish CF population, even though the majority of patients attend the same CF clinic on a regular basis.

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References

  1. Isles A, Maclusky I, Corey M, Gold R, Probert C, Fleming R, Levison H:Pseudomonas cepacia infection in cystic fibrosis: an emerging problem. Journal of Pediatrics 1984, 104: 206–210.

    PubMed  Google Scholar 

  2. Thomassen MJ, Demko CA, Klinger JD, Stern RC:Pseudomonas cepacia colonisation among patients with cystic fibrosis. American Review of Respiratory Diseases 1985, 131: 791–796.

    Google Scholar 

  3. Govan JRW, Brown PH, Maddison J, Doherty CJ, Nelson JW, Dodd M, Greening AP, Webb AK: Evidence for transmission ofPseudomonas cepacia by social contact in cystic fibrosis. Lancet 1993, 342: 15–19.

    PubMed  Google Scholar 

  4. Smith DL, Gumery LB, Smith EG, Stableforth DE, Kauffmann ME, Pitt TL: Epidemic ofPseudomonas cepacia in an adult cystic fibrosis unit: evidence of person-to-person transmission. Journal of Clinical Microbiology 1993, 31: 3017–3022.

    PubMed  Google Scholar 

  5. Fisher MC, LiPuma JJ, Darsen SE, Caputo GC, Mortensen JE, McGowan KL, Stull TL: Source ofPseudomonas cepacia: ribotyping of isolates from patients and from the environment. Journal of Pediatrics 1993, 123: 745–747.

    PubMed  Google Scholar 

  6. Steinbach S, Sun L, Jiang R-Z, Flume P, Gilligan P, Egan TM, Goldstein R: Transmissibility ofPseudomonas cepacia infection in cystic fibrosis patients and lung-transplant recipients with cystic fibrosis. New England Journal of Medicine 1994, 331: 981–987.

    PubMed  Google Scholar 

  7. Pegues DA, Carson LA, Tablan OC, Fitzsimmons SC, Roman SB, Miller JM, Jarvis WR, and the Summer Camp Study Group: Acquisition ofPseudomonas cepacia at summer camps for patients with cystic fibrosis. Journal of Pediatrics 1994, 124: 694–702.

    PubMed  Google Scholar 

  8. Ryley HC, Millar-Jones L, Paull A, Weeks J: Characterisation ofBurkholderia cepacia from cystic fibrosis patients living in Wales by PCR ribotyping. Journal of Medical Microbiology 1995, 43: 436–441.

    PubMed  Google Scholar 

  9. Nir M, Johansen HK, Høiby N: Low incidence of pulmonaryPseudomonas cepacia infection in Danish cystic fibrosis patients. Acta Paediatrica 1992, 81: 1042–1043.

    PubMed  Google Scholar 

  10. Kostman JR, Edlund TD, LiPuma JJ, Stull TL: Molecular epidemiology ofPseudomonas cepacia determined by polymerase chain reaction ribotyping. Journal of Clinical Microbiology 1992, 30: 2084–2087.

    PubMed  Google Scholar 

  11. Grotheus D, Koopman U, von der Hardt H, Tümmler B: Genome fingerprinting ofPseudomonas aeruginosa indicates colonization of cystic fibrosis siblings with closely related strains. Journal of Clinical Microbiology 1988, 26: 1973–1977.

    PubMed  Google Scholar 

  12. Ojeniyi B, Høiby N, Rosdahl VT: Genome fingerprinting as a typing method used on polyagglutinablePseudomonas aeruginosa isolates from cystic fibrosis patients. APMIS 1991, 99: 492–498.

    PubMed  Google Scholar 

  13. Ojeniyi B, Steen Petersen U, Høiby N: Comparison of genome fingerprinting with conventional typing methods used onPseudomonas aeruginosa isolates from cystic fibrosis patients. APMIS 1993, 101: 168–175.

    PubMed  Google Scholar 

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Ryley, H.C., Ojeniyi, B., Høiby, N. et al. Lack of evidence of nosocomial cross-infection byBurkholderia cepacia among danish cystic fibrosis patients. Eur. J. Clin. Microbiol. Infect. Dis. 15, 755–758 (1996). https://doi.org/10.1007/BF01691967

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  • DOI: https://doi.org/10.1007/BF01691967

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