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Occurrence of yeast bloodstream infections between 1987 and 1995 in five Dutch university hospitals

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Abstract

The aim of this study was to identify retrospectively trends in fungal bloodstream infections in The Netherlands in the period from 1987 to 1995. Results of over 395,000 blood cultures from five Dutch university hospitals were evaluated. Overall, there were more than 12 million patient days of care during the nine-year study period. The rate of candidemia doubled in the study period, reaching an incidence of 0.71 episodes per 10,000 patient days in 1995. The general increase in candidemia was paralleled by an increase in non-Candida albicans bloodstream infections, mainly due toCandida glabrata. However, more than 60% of the infections were caused byCandida albicans. Fluconazoleresistant species such asCandida krusei did not emerge during the study period. The increasing rate of candidemia found in Dutch university hospitals is similar to the trend observed in the USA, but the rate is lower and the increase is less pronounced.

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Authors and Affiliations

  1. Department of Medical Microbiology, University Hospital Nijmegen, 440 MMB, P.O. Box 9101, 6500, HB Nijmegen, The Netherlands

    A. Voss, J. A. A. Hoogkamp-Korstanje & J. F. G. M. Meis

  2. Department of Bacteriology, University Hospital Rotterdam, Dr. Molewaterplein 40, 3015, GD Rotterdam, The Netherlands

    J. A. J. W. Kluytmans, H. A. Verbrugh & M. C. Vos

  3. Department of Medical Microbiology, University Hospital Amsterdam (VU), P.O. Box 7057, 1004, MB Amsterdam, The Netherlands

    J. G. M. Koeleman & C. M. J. E. Vandenbroucke-Grauls

  4. Department of Bacteriology, University Hospital Amsterdam (AMC), Meibergdreef 9, 1105, AZ Amsterdam, The Netherlands

    L. Spanjaard

  5. Department of Medical Microbiology, University Hospital Utrecht, Heidelberglaan 100, 3584, CX Utrecht, The Netherlands

    A. Y. L. Weersink

Authors
  1. A. Voss
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  2. J. A. J. W. Kluytmans
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  3. J. G. M. Koeleman
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  4. L. Spanjaard
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  5. C. M. J. E. Vandenbroucke-Grauls
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  6. H. A. Verbrugh
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  7. M. C. Vos
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  8. A. Y. L. Weersink
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  9. J. A. A. Hoogkamp-Korstanje
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  10. J. F. G. M. Meis
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Additional information

For the Workgroup of Hospital infection Epidemiology of the Netherlands (WHEN), University Hospitals of Amsterdam, Nijmegen, Rotterdam, and Utrecht.

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Voss, A., Kluytmans, J.A.J.W., Koeleman, J.G.M. et al. Occurrence of yeast bloodstream infections between 1987 and 1995 in five Dutch university hospitals. Eur. J. Clin. Microbiol. Infect. Dis. 15, 909–912 (1996). https://doi.org/10.1007/BF01690507

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  • DOI: https://doi.org/10.1007/BF01690507

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