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Translobular uptake patterns of environmental toxicants in the rat liver

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  1. Bradford WL, Nakatsugawa T (1982) Perfusion analysis of periportal and centrilobular metabolism of paraoxon in the rat liver. Pestic Biochem Physiol 18:298–303

    Google Scholar 

  2. Crummett WB, Stehl RH (1973) Determination of chlorinated dibenzo-p-dioxins and dibenzofurans in various materials. Environ Health Perspect 5:15–25

    PubMed  Google Scholar 

  3. Eisenbrand J, Baumann K (1969) Water-solubility of 3,4-benzopyrene and formation of a water-soluble complex with caffeine. Z Lebensm Unters Forsch 140:158–163

    Google Scholar 

  4. Murakami N, Uchida M, Sugimoto T, Nakatsugawa T (1987) Relationship between translobular migration in perfused rat liver and hydrophobicity of dialkyl dithiolanylidenemalonates and related compounds. Xenobiotica 17:241–249

    PubMed  Google Scholar 

  5. Nakatsugawa T, Bradford WL, Usui K (1980) Hepatic disposition of parathion: Uptake by isolated hepatocytes and Chromatographie translobular migration. Pestic Biochem Physiol 14:13–25

    Google Scholar 

  6. Tsuda S, Sherman W, Rosenberg A, Timoszyk J, Becker JM, Keadtisuke S, Nakatsugawa T (1987) Rapid periportal uptake and translobular migration of parathion with concurrent metabolism in the rat liverin vivo. Pestic Biochem Physiol 28:201–215

    Google Scholar 

  7. Verschueren K (1983) Handbook of Environmental Data on Organic Chemicals. 2nd Ed., Van Nostrand Reinhold Co., New York

    Google Scholar 

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Correspondence to Tsutomu Nakatsugawa.

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Tsuda, S., Rosenberg, A. & Nakatsugawa, T. Translobular uptake patterns of environmental toxicants in the rat liver. Bull. Environ. Contam. Toxicol. 40, 410–417 (1988).

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  • Waste Water
  • Water Management
  • Water Pollution
  • Uptake Pattern
  • Environmental Toxicant