Biotransformations of α-terpineol in the rat: Its effects on the liver microsomal cytochrome P-450 system

  • K. Madhava Madyastha
  • V. Srivatsan
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References

  1. Chadha A, Madyastha KM (1982) w-Hydroxylation of acyclic monoterpene alcohols by rat lung microsomes. Biochem Biophys Res Commun 108:1271–1277PubMedGoogle Scholar
  2. Chadha A, Madyastha KM (1984) Metabolism of geraniol and linalool in the rat and effects on liver and lung microsomal enzymes. Xenobiotica 14:365–374PubMedGoogle Scholar
  3. Cinti DL, Lemelin MA, Christian J (1976) Induction of liver microsomal mixed-function oxidases by volatile hydrocarbons. Biochem Pharm 25:100–103PubMedGoogle Scholar
  4. Horning MG, Butler CM, Stafford M, Stillwell RN, Hill RM, Zion TE, Harvey DJ, Stillwell WG (1976) In: Advances in mass spectrometry in biochemistry and medicine (Eds Frigerio A, Catagnoli N). Spectrum Publications New York Vol 1, p 91Google Scholar
  5. Ishida T, Asakawa Y, Takemoto T, Aratani T (1981) Terpenoids biotransformation in mammals III: Biotransformation of α-pinene, β-pinene, pinane, 3-carene, carane, myrcene and p-cymene in rabbits. J Pharm Sci 70: 406–415PubMedGoogle Scholar
  6. Jarvisalo J, Vainio N (1980) Enhancement of hepatic drug biotransformation by a short-term intermittent turpentine exposure in rat. Acta Pharmacol Toxicol 46: 32–36.Google Scholar
  7. Jori A, Bianchetti A, Prestini PE (1969) Effect of essential oils on drug-metabolism. Biochem Pharmac 18:2081–2085Google Scholar
  8. Kodama R, Noda K. Ide H (1974) Studies on the metabolism of d-limonene. II The metabolic fate of d-limonene in rabbits. Xenobiotica 4:85–95Google Scholar
  9. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with Folin phenol reagent. J Biol Chem 193:265–275PubMedGoogle Scholar
  10. Lu AYH, Levin W (1972) Partial purification of cytochrome P-450 and P-448 from rat liver microsomes. Biochem Biophys Res Commun 46:1334–1339PubMedGoogle Scholar
  11. Madyastha KM, Renganathan V (1983) Biodegradation of acetates of geraniol, nerol and citronellol byP.incognita: Isolation and identification of metabolites. Indian J Biochem Biophys 20:136–140PubMedGoogle Scholar
  12. Madyastha KM, Renganathan V (1984) Metabolism of (α-terpineol byP.incognita. Can J Microbiol 30:1429–1436PubMedGoogle Scholar
  13. Madyastha KM, Chadha A (1986) Metabolism of 1,8-cineole in rat. Its effects on liver and lung microsomal cytochrome P-450 systems. Bull Environ Contam Toxicol 37:759–766PubMedGoogle Scholar
  14. Omura T, Sato R (1964) The carbon monoxide-binding pigment of liver microsomes. J Biol Chem 239:2370–2378PubMedGoogle Scholar
  15. Parke DV, Rahman H (1969) The effects of some terpenoids and other dietry anutrients on hepatic drug-metabolizing enzymes. Biochem J 113:12PGoogle Scholar
  16. Shukla OP, Moholay MN, Bhattacharyya PK (1968) Fermentation of α- and β-pinenes by a soil pseudomonad. Indian J Biochem 5:79–91Google Scholar
  17. Ventura P, Schiavi M, Serafini S, Selva A (1985) Further studies of trans-sobrerol metabolism: rat, dog and human urine. Xenobiotica 15:317–325PubMedGoogle Scholar

Copyright information

© Springer-Verlag New York Inc. 1988

Authors and Affiliations

  • K. Madhava Madyastha
    • 1
  • V. Srivatsan
    • 1
  1. 1.Bio-Organic Section, Department of Organic ChemistryIndian Institute of ScienceBangaloreIndia

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