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Mucin histochemistry of submandibular and parotid salivary glands of man: Light and electron microscopy

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Summary

Light-microscopy showed parotid serous acinar cells to contain neutral mucin, serous and mucous acinar cells of submandibular gland and intercalary ductal cells of both glands to contain acid and neutral mucins, and cells of striated ducts and excretory ducts to contain neutral mucin. Mucins were demonstrated ultrastructurally in a portion of the components of secretory granules of acinar cells and intercalary ductal cells, and in secretory granules of striated and excretory ductal cells. The mucins were all stained by techniques that reveal 1,2-glycols. Secretory granules of submandibular mucous and serous acinar cells and intercalary ductal cells were stained variably by the low irondiamine technique for acid mucin, and those of mucous acinar cells by the high iron-diamine technique for sulphomucins. A variable component of the secretory granules of acinar and intercalary ductal cells did not contain demonstrable mucin and possibly consisted of protein. The results suggest that one type of cell may be able to produce a range of secretory products and to package them variously into secretory granules.

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Authors and Affiliations

  1. Department of Oral Pathology, The Rayne Institute, King's College School of Medicine and Dentistry, 123 Coldharbour Lane, SE5 9NU, London, UK

    J. D. Harrison, D. W. Auger, Katherine L. Paterson & P. S. A. Rowley

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  1. J. D. Harrison
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  2. D. W. Auger
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  3. Katherine L. Paterson
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  4. P. S. A. Rowley
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Harrison, J.D., Auger, D.W., Paterson, K.L. et al. Mucin histochemistry of submandibular and parotid salivary glands of man: Light and electron microscopy. Histochem J 19, 555–564 (1987). https://doi.org/10.1007/BF01687363

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  • DOI: https://doi.org/10.1007/BF01687363

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