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The effect of lead and cadmium on liver, kidney, and brain levels of cadmium, copper, lead, manganese, and zinc, and on erythrocyte ALA-D activity in mice

Summary

Lead and cadmium were administered intraperitoneally, singly and jointly, to the mice. The levels of cadmium, copper, manganese, lead and zinc were determined in liver, kidney and brain by atomic absorption spectrophotometric technique and deltaaminolevulinic acid dehydratase (ALA-D) activity was determined in erythrocytes. The tissue levels of some of these metals were found significantly altered by cadmium and lead both, but cadmium was found to have no effect on blood on ALA-D activity.

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Seth, T.D., Agarwal, L.N., Satija, N.K. et al. The effect of lead and cadmium on liver, kidney, and brain levels of cadmium, copper, lead, manganese, and zinc, and on erythrocyte ALA-D activity in mice. Bull. Environ. Contam. Toxicol. 16, 190–196 (1976). https://doi.org/10.1007/BF01685226

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Keywords

  • Cadmium
  • Aminolevulinic Acid
  • Cadmium Acetate
  • Acid Dehydratase
  • Manganese Level