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Polychlorinated biphenyl-induced decrease in liver vitamin A in Japanese quail and rats

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Summary

‘Aroclor 1242’ (PCB) or DDT increased liver weight and lipids and decreased liver vitamin A of male and female rats or male Japanese quail. Laying female quail did not show consistent changes, presumably due to mobilization of lipid and vitamin A for egg yolk. When egg laying was inhibited, PCB reduced liver vitamin A 50%. ‘Aroclor 1242’ reduced egg production, but had no effect on egg weight or eggshell thickness.

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Cecil, H.C., Harris, S.J., Bitman, J. et al. Polychlorinated biphenyl-induced decrease in liver vitamin A in Japanese quail and rats. Bull. Environ. Contam. Toxicol. 9, 179–185 (1973). https://doi.org/10.1007/BF01685000

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