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Embryotoxic effects of three PCB's in the chicken


Injection of Arochlor 1242 into chicken eggs on day 0 of incubation severely limited hatchability at levels above 2.5 ppm. The 1254 and 1260 isomers were less effective in this respect, requiring 10 ppm or more. Embryonic mortality occurred during the period of organ formation suggesting an effect on inductive mechanisms. This is supported by observation of several malformations in chicks that developed until day 21. The effects induced by the day 0 injections of the 1242 isomer are permanent as growth rates were severely depressed during the 2 week period following hatching.

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  1. FLICK, D.F., O'DELL, R.G. and CHILDS, V.A., Poult. Sci.44, 1460 (1965)

    PubMed  Google Scholar 

  2. PICHIRALLO, J., Science173, 899 (1971)

    Google Scholar 

  3. RISEBROUGH, R.W., RIECHE, P., PEAKALL, D.B., HERMAN, S.G. and KIRVEN, M.N., Nature220, 1098 (1968)

    PubMed  Google Scholar 

  4. SCOTT, M.L., VADEHRA, D.V., MULLENHOFF, P.A., RUMSEY, G.L. and RICE, R.W., Proc. 1971 Cornell Nutrition Conf. for Feed Manufacturers, Nov. 2–4, 1971

  5. WASSERMANN, D., WASSERMANN, M., DJAVAHERIAN, M., GORIN, I., BARISH, M. and TAVOR, R., Bull. of Env. Contam. and Toxicol.6, 1 (1971)

    Google Scholar 

  6. ZITKO, V., CHOI, P.M.K., Bull. of Env. Contam. and Toxicol.7, 1 (1972)

    Google Scholar 

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Carlson, R.W., Duby, R.T. Embryotoxic effects of three PCB's in the chicken. Bull. Environ. Contam. Toxicol. 9, 261–266 (1973).

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  • Growth Rate
  • Waste Water
  • Water Management
  • Water Pollution
  • Organ Formation