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Detection of human herpesviruses 6 and 7 in heart transplant recipients by a multiplex polymerase chain reaction method

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Abstract

In order to evaluate the possible reactivation of human herpesviruses 6 (HHV-6) and 7 (HHV-7) after heart transplantation, buffy-coat and plasma specimens from 21 transplant patients and 56 healthy blood donors were examined for HHV-6 and HHV-7 DNA by polymerase chain reaction. Human herpesvirus 6 and HHV-7 infection or reactivation has been suggested to play a role in cytomegalovirus disease progression in renal transplant recipients. In the present study, however, no significant difference in the prevalence of HHV-6 and HHV-7 was found between the immunosuppressed and the healthy population; moreover, no viral reactivation was found in the heart transplant recipients.

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Authors and Affiliations

  1. Sezione di Microbiologia, Dipartimento di Biologia Molecolare, Università di Siena, Via Laterina 8, I-53100, Siena, Italy

    D. Moschettini, A. De Milito, M. Catucci, A. Marconi, C. Rinina, M. L. Bianchi-Bandinelli & P. E. Valensin

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  1. D. Moschettini
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  2. A. De Milito
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  3. M. Catucci
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  4. A. Marconi
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  5. C. Rinina
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  6. M. L. Bianchi-Bandinelli
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  7. P. E. Valensin
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Moschettini, D., De Milito, A., Catucci, M. et al. Detection of human herpesviruses 6 and 7 in heart transplant recipients by a multiplex polymerase chain reaction method. Eur. J. Clin. Microbiol. Infect. Dis. 17, 117–119 (1998). https://doi.org/10.1007/BF01682168

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  • DOI: https://doi.org/10.1007/BF01682168

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