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Tolerance to the mydriatic effects of morphine in mice

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Summary

When injected to mice, opiates produce mydriasis. Animals treated chronically with morphine, developed tolerance to the mydriatic effects of morphine. The degree and consistency of the response make the pupil a valuable tool in opiate research.

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References

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Author notes

  1. A. D. Korczyn

    Present address: Department of Physiology and Pharmacology, Sackler School of Medicine, Ramat Aviv, Israel

Authors and Affiliations

  1. Department of Physiology and Pharmacology, Sackler School of Medicine, Ramat Aviv, Israel

    C. Adler & O. Keren

  2. Department of Neurology, Beilinson Hospital, Ramat Aviv, Israel

    C. Adler, O. Keren & A. D. Korczyn

  3. Maurice and Gabriela Goldschleger Eye Institute, Tel Aviv University, Ramat Aviv, Israel

    C. Adler, O. Keren & A. D. Korczyn

Authors
  1. C. Adler
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  2. O. Keren
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  3. A. D. Korczyn
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Adler, C., Keren, O. & Korczyn, A.D. Tolerance to the mydriatic effects of morphine in mice. J. Neural Transmission 48, 43–47 (1980). https://doi.org/10.1007/BF01670032

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  • DOI: https://doi.org/10.1007/BF01670032

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