Synthesis and X-ray structure of new 5-amino-methyl-4-isoxazolecarboxylic acid azides

Abstract

The syntheses of the new heterocyclic azides which open a number ways of obtaining interesting isoxazole derivatives has been described. Chemical, spectral and X-ray data giving the evidence of the structure of these compounds are presented. X-ray studies were carried out on compoundsI,II(C₅H₅N₅O₂, C₁₂H₉N₅O₃) witha=3.775(2), 7.179(3);b=11.593(3), 8.135(3);c=8.443(3), 11.610(3);Z=2, 2 and space group Pn,$P\bar 1$. The structure was established using direct methods and refined by weighted full-matrix least squares. The refinement, based on 687 reflections forI, and 1648 forII withI>/σ 3.0 (I), converged to a finalR of 0.333, 0.034 andR _w=0.036, 0.032.