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  • International Association of Endocrine Surgeons—Manuscripts Presented at the 31st Congress of the International Society of Surgery
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Secretory pattern and blood pressure in pheochromocytoma

World Journal of Surgery volume 10, pages 724–727 (1986)Cite this article

Abstract

The diagnostic accuracy of urinary and plasma catecholamines was studied in 16 patients with pheochromocytoma. Five of 16 patients had 1 or more plasma samples within the normal range, while all 16 patients had increased urinary samples. Urinary catecholamines, therefore, have a higher diagnostic specificity than plasma catecholamines. No diurnal rhythm of catecholamine secretion was found in 7 patients in whom plasma catecholamines and blood pressure were followed for 24 hours. No correlation was found between blood pressure and plasma catecholamines in patients at rest.

Résumé

La précision du diagnostic apportée par le dosage des catécholamines dans le plasma et les urines a été étudiée chez 16 malades qui présentaient un phéochromocytome. Chez 5 d'entre eux les dosages dans un ou plusieurs échantillons de plasma étaient normaux alors que le taux des catécholamines était élevé dans les échantillons d'urine. Il apparaît ainsi que les dosages urinaires ont une spécificité diagnostique supérieure à celle des dosages plasmatiques. Aucun rythme diurne de la sécrétion des catécholamines ne fut découvert chez 7 sujets chez qui les catécholamines plasmatiques et la pression artérielle furent suivis au cours de 24 heures. Aucune corrélation ne fut constatée entre la pression artérielle et les catécholamines plasmatiques chez les subjets au repos.

Resumen

La precisión diagnóstica del nivel de catecolaminas urinarias y plasmáticas fue estudiada en 16 pacientes con feocromocitoma. Cinco de 16 pacientes exhibieron una o más determinaciones plasmáticas dentro de limites normales, en tanto que todas las determinaciones en orina aparecieron elevadas. Por consiguiente, se puede afirmar que las catecolaminas urinarias poseen una más alta especificidad diagnóstica que las catecolaminas plasmáticas. No se encontró ritmo diurno de secreción de catecolaminas en 7 pacientes en quienes se determinaron las catecolaminas plasmáticas y la presión arterial durante períodos de 24 horas. No se encontró correlación entre la presión arterial y el nivel de catecolaminas plasmáticas en los pacientes en reposo.

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Author information

Affiliations

  1. Department of Surgery, Karolinska Hospital, S-104 01, Stockholm, Sweden

    Staffan Gröndal M.D., Bertil Hamberger M.D. & Margaretha Telenius-Berg M.D.

  2. Department of Internal Medicine, Hässleholm, Sweden

    Staffan Gröndal M.D., Bertil Hamberger M.D. & Margaretha Telenius-Berg M.D.

Authors
  1. Staffan Gröndal M.D.
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  2. Bertil Hamberger M.D.
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  3. Margaretha Telenius-Berg M.D.
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Supported by the Swedish Medical Research Council (02330) and Karolinska Institute.

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Gröndal, S., Hamberger, B. & Telenius-Berg, M. Secretory pattern and blood pressure in pheochromocytoma. World J. Surg. 10, 724–727 (1986). https://doi.org/10.1007/BF01655568

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  • DOI: https://doi.org/10.1007/BF01655568

Keywords

  • Blood Pressure
  • Cardiac Surgery
  • Catecholamine
  • Urinary Sample
  • Diagnostic Accuracy