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Cervical exploration for suspected primary hyperparathyroidism in renal stone formers: A challenge to the surgeon

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Abstract

A retrospective analysis of 579 patients operated on for suspected primary hyperparathyroidism (PHPT) shows that male stone formers are younger, have less hypercalcemia, fewer neuromuscular symptoms, and a higher frequency of parathyroid hyperplasia or normal findings than men without renal stones. On the other hand, female stone formers do not differ from female patients without renal stones with regard to age, degree of hypercalcemia, or preoperative symptoms, but, like the male stone formers, they have a higher frequency of hyperplasia. This circumstance means that female as well as male patients present special problems at cervical exploration.

Résumé

L'analyse rétrospective de 579 patients opérés d'hyperparathyroïdisme primitif a montré que, chez les patients mâles, ceux qui présentaient une lithiase urinaire comparés à ceux qui n'en présentaient pas, étaient plus jeunes, avaient une hypercalcémie moindre, des symptômes neuromusculaires moins nombreux et une fréquence d'hyperplasie plus élevée ou pas de lésion parathyroïde. En revanche, chez les femmes, avec ou sans lithiase urinaire, il n'y avit pas de différence significative selon l'âge, le degré d'hypercalcémie ou les symptômes préopératoires. Mais, comme chez les hommes, la fréquence de l'hyperplasie était plus grande chez les femmes lithiasiques que chez celles qui ne l'étaient pas. Nous concluons qu'à l'exploration cervicale pour hyperparathyroïdisme, les femmes posent autant de problèmes que les hommes.

Resumen

Un análisis retrospectivo de 579 pacientes operados por probable hiperparatiroidismo primario muestra que el hombre formador de cálculos es más joven, exhibe menor hipercalcemia, menos síntomas neuromusculares, y una mayor frecuencia de hiperplasia paratiroidea o de hallazgos normales que aquellos libres de cálculos. Por el contrario, las mujeres formadoras de cálculos no difieren de las libres de cálculos en cuanto a edad, grado de hipercalcemia, o síntomas preoperatorios, pero al igual que los hombres formadores de cálculos ellas exhiben una mayor frecuencia de hiperplasia. Esto quiere decir que tanto la mujer como el hombre presentan problemas especiales en cuanto a la exploración cervical en probable hiperparatiroidismo primario en pacientes formadores de cálculos.

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Farnebo, L.O., Sandersjöö, G. & Granberg, P.O. Cervical exploration for suspected primary hyperparathyroidism in renal stone formers: A challenge to the surgeon. World J. Surg. 12, 534–536 (1988). https://doi.org/10.1007/BF01655443

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  • DOI: https://doi.org/10.1007/BF01655443

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