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Stump cancer following gastric surgery

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Abstract

This paper reviews the literature regarding the development of gastric cancer in the stomach remnant following gastric resection. Although there is as yet little supporting experimental evidence, clinical studies suggest that the risk of developing gastric cancer is increased, perhaps as much as 6-fold, following partial gastrectomy for benign lesions. It also appears that the risk of developing cancer is greatest if the lesion for which the gastrectomy was originally performed was a gastric ulcer rather than a duodenal ulcer. The type of gastrectomy does not seem to influence this increased risk. Hypotheses are reviewed concerning the role of changes in gastric morphology following partial gastrectomy in the development of cancer.

Résumé

Revue de la littérature concernant le développement d'un cancer dans le moignon gastrique après gastrectomie subtotale. Malgré l'absence de preuve expérimentale, les études cliniques suggèrent que le risque d'apparition d'un cancer est accru, peutêtre jusqu'à 6 fois, après gastrectomie pour lésion bénigne. Le risque semble être également plus élevé après gastrectomie pour ulcère gastrique que pour ulcère duodénal. Le type de résection gastrique n'a aucune influence. Diverses hypothèses ont été émises concernant les altérations postopératoires de la morphologie gastrique et leur rôle possible dans le développement du cancer: ces hypothèses sont revues.

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References

  1. Freeman, M.A., Berne, C.J.: Gastric carcinoma of gastrojejunal stoma. Gastroenterology27:210, 1954

    Google Scholar 

  2. Peters, H., Schubert, H.J., Reifferscheid, M.: Das carcinoma in Restmagen nach Resektion wegen gutartiger Befunde. Langenbecks Arch. Chir.336:219, 1974

    Google Scholar 

  3. Reynolds, K.W., Johnson, A.G., Fox, B.: Is intestinal metaplasia of the gastric mucosa a pre-malignant lesion? Clin. Oncol.1:101, 1975

    Google Scholar 

  4. Lawson, H.H.: Effect of duodenal contents on the gastric mucosa. S. Afr. J. Surg.3:79, 1965

    Google Scholar 

  5. Gough, D.C., Craven, J.L.: Presentation to British Society of Gastro-enterology. Gut16:843, 1975

    Google Scholar 

  6. Nicholls, J.C.: Carcinoma of the stomach following partial gastrectomy for benign gastroduodenal lesions. Br. J. Surg.61:244, 1974

    Google Scholar 

  7. Swynnerton, B.F.A., Tanner, N.C.: Chronic gastric ulcer—a comparison between a gastroscopically controlled series treated medically and a series treated by surgery. Br. Med. J.2:841, 1953

    Google Scholar 

  8. Helsingen, N., Hillestad, L.: Cancer development in the gastric stump after partial gastrectomy for ulcer. Ann. Surg.143:173, 1956

    Google Scholar 

  9. Taksdal, S., Stalsberg, H.: Histology of gastric carcinoma occurring after gastric surgery for benign conditions. Cancer32:162, 1973

    Google Scholar 

  10. Morgenstern, L., Vamakawa, T., Seltzer, D.: Carcinoma of the gastric stump. Am. J. Surg.125:29, 1973

    Google Scholar 

  11. Saegesser, F., James, D.: Cancer of the gastric stump after partial gastrectomy for ulcer (Billroth II principle) for ulcer. Cancer29:1150, 1972

    Google Scholar 

  12. Hofstetter, J.R., Realini, S., Fasel, J., Arnold, J., Saegesser, F.: Cancer du magnon gastrique après resection pour ulcère bénin. Praxis64:1472, 1975

    Google Scholar 

  13. Debray, V.C., Bouvry, M., Roches, P.: Stump carcinoma after gastric resection for ulcer. Schweiz. Med. Wochenschr.88:631, 1958

    Google Scholar 

  14. De Jode, L.R.: Gastric carcinoma following gastroenterostomy and partial gastrectomy. Br. J. Surg.48:512, 1961

    Google Scholar 

  15. Doll, R., Avery-Jones, F., Buchatzsch, M.M.: Special report to Ser. Med. Res. Council, London. No. 276, 1951

  16. Hilbe, G., Salzer, G.M., Hussl, H., Kutschera, H.: The incidence of cancer in the gastric remnant after subtotal gastric resection. Arch. Klin. Chir.323:142, 1968

    Google Scholar 

  17. Stalsberg, H.: Stomach cancer and previous gastric surgery. Gastroenterology62:1276, 1972

    Google Scholar 

  18. Stalsberg, H.: Stomach cancer following gastric surgery for benign conditions. Lancet2:1175, 1971

    Google Scholar 

  19. Skinner, J.M., Heenan, P.J., Whitehead, R.: Atrophic gastritis in gastrectomy specimens. Br. J. Surg.62:23, 1975

    Google Scholar 

  20. Duplessis, D.J.: The distribution of gastritis in carcinoma of the stomach. Br. J. Surg.61:521, 1974

    Google Scholar 

  21. Lagache, G., Vankemmel, M.: Cancer of the gastric stump following gastrectomy for ulcer. Arch. Chir.20:618, 1966

    Google Scholar 

  22. Montgomery, R.D., Richardson, B.P.: Gastric ulcer and cancer. Q. J. Med.44:591, 1975

    Google Scholar 

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Nicholls, J.C. Stump cancer following gastric surgery. World J. Surg. 3, 731–734 (1979). https://doi.org/10.1007/BF01654802

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