Summary
We reviewed retrospectively the clinical records of patients with non-typhi Salmonella bacteraemia in our hospital from 1979 to 1988. During the study period 45 non-typhi Salmonella bacteraemias were diagnosed in 43 patients. Ten patients were under one year old and 11 were over 60. Seven cases of sepsis presented in patients with AIDS. Only three episodes were nosocomially acquired. In two of three patients the bacteraemia was preceded by an episode of acute gastroenteritis and one third presented without gastroenteritis. Complications and mortality were infrequent in spite of the differing degrees of adequacy of antibiotic treatment which was inappropriate in many cases. We have attempted to assess optimal antibiotic therapy, taking into account the duration and means of administration, in different groups of patients with non-typhi Salmonella bacteraemia.
Zusammenfassung
Bakteriämien durch Salmonellen, die zwischen 1979 und 1988 in unserem Krankenhaus auftraten, wurden retrospektiv untersucht. Bei 43 Patienten waren 45 Fälle von Bakteriämie durch Salmonellen (S typhi ausgenommen), diagnostiziert worden. Zehn Patienten waren jünger als ein Jahr, elf älter als 60. Sieben Sepsisfälle waren bei AIDS-Kranken aufgetreten. Nur in drei Fällen handelte es sich um eine nosokomiale Infektion. In zwei Fällen war eine akute Gastroenteritis vorausgegangen, der dritte Fall verlief ohne Gastroenteritis. Trotz der schwankenden Qualität der Antibiotikatherapie, die in vielen Fällen unzureichend war, traten Komplikationen selten auf, die Mortalität war gering. Es wird ein Vorschlag zur Optimierung der Antibiotikatherapie bei nicht durchS. typhi verursachter Salmonellen-Bakteriämie unter Berücksichtigung der Therapiedauer, des Applikationsmodus und der Unterschiede in den betroffenen Patientengruppen gemacht.
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Bassa, A., Parras, F., Reina, J. et al. Non-typhi Salmonella bacteraemia. Infection 17, 290–293 (1989). https://doi.org/10.1007/BF01650710
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DOI: https://doi.org/10.1007/BF01650710