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24-Stunden-Blutdruckmessungen im Verlauf der normalen Schwangerschaft und bei hypertensiven Schwangeren

24-Hour ambulatory blood pressure measurements in normotensive pregnancy and in preeclampsia

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Summary

Noninvasive 24-hour ambulatory blood pressure monitoring was performed in 17 normotensive and 19 preeclamptic pregnant women. The normotensive women showed a significant nightly decline in their systolic and diastolic blood pressure. In contrast, the preeclamptic women demonstrated either an attenuated circadian rhythm or no circadian rhythm at all. This result was even more pronounced in patients with severe hypertension, some of whom had a nocturnal increase in blood pressure in spite of being treated with antihypertensive drugs in an evening dose. The lack of nocturnal blood pressure decrease was also found 24 hours post partum.

In summary, these results suggest that preeclamptic women are endangered by hypertensive emergencies mostly during the night. Therefore blood pressure controls should be extended into the night, and antihypertensive drugs should also be given in a sufficient evening dose.

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Abbreviations

H:

haemolysis

el:

elevated liver enzymes

lp:

low platelets

SSW:

Schwangerschaftswoche

RR:

Blutdruck

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Herrn Prof. Dr. med. F. Scheler zum 65. Geburtstag gewidmet. Diese Arbeit enthält Teilergebnisse einer noch nicht eingereichten Inaugural-Dissertation von U. Guhlke

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Rath, W., Schrader, J., Guhlke, U. et al. 24-Stunden-Blutdruckmessungen im Verlauf der normalen Schwangerschaft und bei hypertensiven Schwangeren. Klin Wochenschr 68, 768–773 (1990). https://doi.org/10.1007/BF01647246

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  • DOI: https://doi.org/10.1007/BF01647246

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