The use of polyglactin 910 (Vicryl®) in colonic anastomoses is theoretically undesirable because its short dissolution time and multifilament structure may lead to local sepsis and anastomotic leakage. We have compared Vicryl with a newly introduced monofilament absorbable suture which has a longer dissolution time than Vicryl. In a study of 98 rat colonic anastomoses no difference was found in complication rates or cellular reaction to the suture material between Vicryl and polydioxanone (PDS®). The use of monofilament suture with longer dissolution time does not necessarily imply added security for colonic anastomoses.
This is a preview of subscription content, access via your institution.
Buy single article
Instant access to the full article PDF.
Price excludes VAT (USA)
Tax calculation will be finalised during checkout.
Khoury GA, Waxman BP (1983) Large bowel anastomosis. The healing process and sutured anastomosis. A review. Br J Surg 70:61–63
Durdey P, Bucknall TE (1984) Assessment of sutures for use in colonic surgery, an experimental study. J R Soc Med 77:472–477
Ray JA, Doddi N, Regula D, Williams JA, Melveger A (1981) Polydioxanone (PDS), a novel monofilament synthetic absorbable suture. Surg Gynecol Obstet 153:497–507
Craig PH, Williams JA, Davis KW, Magoun AD, Levy AJ, Bogdansky S, Jones JP (1975) A biologic comparison of polyglactin 910 and polyglycolic acid synthetic absorbable sutures. Surgery 141:1–10
Blomstedt B, Østerberg B (1978) Suture materials and wound infection. Acta Chir Scand 144:269–274
Blomstedt B, Østerberg B (1977) Fluid absorption and capillarity of suture materials. Acta Chir Scand 143:197–204
Østerberg B, Blomstedt B (1979) Effect of suture materials on bacterial survival in infected wounds. Acta Chir Scand 145:431–434
Paterson-Brown S, Cheslyn-Curtis S, Biglin J, Dye J, Easmon CSF, Dudley HAF (1987) Suture materials in contaminated wounds: a detailed comparison of a new suture with those currently in use. Br J Surg 74:734–735
Lord MG, Broughton AC, Williams HTG (1978) A morphologic study on the effect of suturing the submucosa of the large intestine. Surg Gynecol Obstet 146:211–216
Houdart R, Lavergne A, Valleur P, Hautefeuille P (1986) Polydioxanone in digestive surgery. An experimental study. Am J Surg 152:268–271
Fontaine CJ, Dudley HAF (1978) Assessment of suture materials for intestinal use by an extramucosal implant technique and a quantitative histological evaluation. Br J Surg 65:288–290
Blomstedt B, Jacobsson SJ (1977) Experiences with polyglactin 910 (Vicryl) in general surgery. Acta Chir Scand 143:259–263
Edlich RF, Panek PH, Rodeheaven GT, Turnbull VG, Kuntz LD, Edgerton MT (1973) Physical and chemical configuration of sutures in the development of surgical infection. Ann Surg 177:679–687
Ching-Chang Chu, Williams DF (1984) Effects of physical configuration and chemical structure of suture materials on bacterial adhesion. A possible link to wound infection. Am J Surg 147:197–204
McGeehan D, Hunt D, Chaudhuri A, Rutter P (1980) An experimental study of the relationship between synergistic wound sepsis and suture materials. Br J Surg 67:636–638
About this article
Cite this article
Andersen, E., Søndenaa, K. & Holter, J. A comparative study of polydioxanone (PDS®) and polyglactin 910 (Vicryl®) in colonic anastomoses in rats. Int J Colorect Dis 4, 251–254 (1989). https://doi.org/10.1007/BF01644992