Literature
Hovadam, V. W., Smilack, J. D., Montgomery, C. L. In vitro activity of N-formimidoyl thienamycin (MK-0787). A crystalline derivative of thienamycin. Antimicrob. Agents Chemother. 18 (1980) 557–561.
Kropp, H., Sundelof, J. G., Hajdu, R. Metabolism of thienamycin and related carbapenem antibiotics by the renal dipeptidase: Dehydropeptidase I. Antimicrob. Agents Chemother. 22 (1982) 62–70.
Kahan, F. M., Kropp, H., Sundelof, J. G., Birnbaum, J. Thienamycin: development of imipenem-cilastatin. J. Antimicrob. Chemother. 12 Suppl. D (1983) 1–35.
Washburn, D. E., Perfect, J. R., Durach, D. T. Pharmacokinetics of N-formimidoyl thienamycin and the influence of a renal depeptidase inhibitor on experimental meningitis. J. Antimicrob. Chemother. 12 (1982) 35–39.
Drusano, G. L., Standiford, H. C., Bustamante, C., Forrest, A., Rivera, G., Leslie, J., Tatem, B., Delaportas, D., MacGregor, R. R., Schimpff, S. C. Multiple-dose pharmacokinetics of imipenemcilastatin. Antimicrob. Agents Chemother. 26 (1984) 715–721.
Freij, B. J., McCracken, G. H., Olsen, K. D., Threlkeld, N. Pharmacokinetics of imipenem-cilastatin in neonates. Antimicrob. Agents Chemother. 27 (1985) 431–435.
Modai, J., Vittecoq, D., Decazes, J. M., Meulemans, A. Penetration of imipenem and cilastatin into cerebrospinal fluid of patients with bacterial meningitis. J. Antimicrob. Chemother. 16 (1985) 751–755.
Myers, C. M., Blumer, J. L. Determination of imipenem and cilastatin in serum by high-pressure liquid chromatography. Antimicrob. Agents Chemother. 26 (1984) 78–81.
Norrby, S. R., Rogers, J. D., Ferber, F., Jones, K. H., Zacchei, A. G., Weidner, L. L., Demetriades, J. L., Gravallese, D. A., Hsieh, J. Y.-K. Disposition of radiolabeled imipenem and cilastatin in normal human volunteers. Antimicrob. Agents Chemother. 26 (1984) 707–714.
Erttmann, M., Krausse, R., Ullmann, U., Hamelmann, H. Determination of serum and tissue levels of imipenem by HPLC. Proceedings of the 14th International Congress of Chemotherapy, Kyo-to 1985, Antimicrobial Section II (1985) 1213–1214.
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Krausse, R., Ullmann, U. Determination of imipenem and cilastatin in serum and tissue by high-pressure liquid chromatography. Infection 14, 243–245 (1986). https://doi.org/10.1007/BF01644271
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DOI: https://doi.org/10.1007/BF01644271