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Evolution in antibiotic susceptibility of bacteroides fragilis group strains in France based on periodic surveys

Resistenzentwicklung bei Stämmen von Bacteroides fragilis in Frankreich. Ergebnis periodischer Kontrollstudien

  • Addendum II
  • The Impact Of Microbiology On Clinical Problem International Symposium Weitenburg/Tübingen, June 1988
  • Published:
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Summary

Anaerobic antibiotic susceptibility testing with standardized methods enabled the authors to speculate on the evolution of antibiotic resistance within theBacteroides fragilis group strains. Cefoxitin resistance was stable (0–5%) until 1985 and gradually increased later. Clindamycin resistance emerged in 1980 with a stable 10% resistance rate until 1986. An increase in clindamycin resistance developed in three institutions in 1987 [14]. No change was detected for imipenem and metronidazole, while piperacillin resistance increased since 1986. A comparison of antibiotic resistance rates is discussed for anaerobes in different countries.

Zusammenfassung

Standardisierte Methoden für die anaerobe Empfindlichkeitsprüfung ermöglichen es den Autoren, Vermutungen über die Entwicklung der Antibiotika-Resistenz innerhalb derBacteroides fragilis-Gruppe anzustellen. Die Cefoxitin-Resistenz war bis 1985 stabil (0–5%) und stieg danach langsam an. Die Clindamycin-Resistenz trat erst 1980 auf mit einer stabilen Resistenzrate von 10% bis 1986. Eine Steigerung der Resistenzraten von Clindamycin trat 1987 bei drei Instituten auf [14]. Keine Änderungen konnten für Imipenem und Metronidazol entdeckt werden, während die Piperacillin-Resistenz seit 1986 zunahm. Es wird ein Vergleich der Antibiotika-Resistenzraten der Anaerobier der verschiedenen Länder diskutiert.

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Authors and Affiliations

  1. Department of Microbiology, Faculty of Pharmacy, University Lille II, France

    L. Dubreuil Ph.D. &  C. Romond Ph.D.

  2. Hotel-Dieu Hospital Nantes, France

    M. Derriennic M.D. &  A. L. Courtieu M.D.

  3. Annecy Hospital, France

    A. Sedallian M.D.

Authors
  1. L. Dubreuil Ph.D.
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  2. C. Romond Ph.D.
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  3. M. Derriennic M.D.
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  4. A. L. Courtieu M.D.
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  5. A. Sedallian M.D.
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Dubreuil, L., Romond, C., Derriennic, M. et al. Evolution in antibiotic susceptibility of bacteroides fragilis group strains in France based on periodic surveys. Infection 17, 197–200 (1989). https://doi.org/10.1007/BF01644030

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