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The last round against bacterial infections?

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References

  1. Westphal, O., Lüderitz, O. Chemische Erforschung von Lipopolysacchariden gramnegativer Bakterien. Angew. Chem. 66 (1954) 407–417.

    Google Scholar 

  2. Westphal, O. Bacterial endotoxins. The 2nd Carl Prausnitz Memorial Lecture. Int. Arch. Allergy Appl. Immun. 49 (1975) 1–43.

    Google Scholar 

  3. Rietschel, E. T., Kim, Y. B., Watson, D. W., Galanos, C., Lüderitz, O., Westphal, O. Pyrogenicity and immunogenicity of lipid A complexed with bovine serum albumin or human serum albumin. Infect. Immun. 8 (1973) 173–177.

    Google Scholar 

  4. McCabe, W. R., Johns, M., Zinner, S. H., Greely, A. Lipopolysaccharides and protection against gram-negative bacterial infections. In:Beers, R. F., Basset, E. G. (eds.): The role of immunological factors in infectious, allergic, and immunological processes. Raven Press, New York 1976, pp. 5–16.

    Google Scholar 

  5. Braude, A. I. Opposing effects of immunity to endotoxin: Hypersensitivity versus protection. In:Urbaschek, B., Urbaschek, R., Neter, E. (eds.): Gram-negative bacterial infections. Springer-Verlag, Wien, New York 1975, pp. 69–74.

    Google Scholar 

  6. Ziegler, E. J., McCutchan, J. A., Fierer, J., Glauser, M. P., Sadoff, J. C., Douglas, H., Braude, A. I. Treatment of gram-negative bacteremia and shock with human antiserum to a mutantEscherichia coli. N. Engl. J. Med. 307 (1982) 1225–1530.

    Google Scholar 

  7. Galanos, C., Lüderitz, O., Westphal, O. Preparations and properties of antisera against the lipid-A component of bacterial lipopolysaccharides. Eur. J. Biochem. 9 (1971) 116–122.

    Google Scholar 

  8. Marget, W., Schüßler, P. Lipopolysaccharides in Crohn's disease. Lancet, July 10 (1976) 97.

    Google Scholar 

  9. Westenfelder, M., Galanos, C., Madsen, P. O., Marget, W.: Pathological activities of lipid A: Experimental studies in relation to chronic pyelonephritis. Microbiol. (1977) 277–279.

  10. Simon, G., Reindke, B., Marget, M. Lipoid A-Antikörpertiter bei Pyelonephritis und anderen Infektionen mit gram-negativen Bakterien. Infection 2 (1974) 178–184.

    Google Scholar 

  11. Mar, P., Marget, W., Schneider, K., Belohradsky, B. H., Roos, R. Relevance of vesico-ureteric reflux in development of lipid A antibodies in recurrent urinary tract infections in children — a preliminary study. Eur. J. Pediatr. 146 (1987) 51–55.

    Google Scholar 

  12. Marget, W. Lipoid A-Antikörpertiter beim Menschen. Infection 15, Suppl. 2 (1987) S85-S88.

    Google Scholar 

  13. Marget, W., Mar, P. J., Jaspers, L. Preliminary study on administration of high-titer lipid A antibody serum in sepsis and septic shock patients. Infection 13 (1985) 120–125.

    Google Scholar 

  14. Jaspers, L., Marget, W., Mar, P. J., Hoffmann, K., Langecker, P., Ruckdeschel, G., Obermeier, A., Kastenbauer, E. Antikörper gegen Lipoid A in der Behandlung des septischen Schocks. Infection 15, Suppl. 2 (1987) S89-S95.

    Google Scholar 

  15. Bogard, W. C. jr., Dunn, D. L., Abernethy, K., Kilgarriff, C., Kung, P. C.: Isolation and characterization of murine monoclonal antibodies specific for gram-negative bacterial lipopolysaccharide: Association of cross-genus reactivity with lipid A specificity. Infection and Immunity, Apr. 1987, pp. 899–908.

  16. Köhler, G., Milstein, C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256 (1975) 495–497.

    Google Scholar 

  17. Young, L. S., Alam, S., Gascon, R.: Monoclonal antibody directed against the core glycolipid of enterobacterial endotoxin. Clin. Res. 30 (1982) 522A.

  18. Gorelick, K.: Randomized multicenter trial of E5 anti-LIPS antibody in patients with gram-negative sepsis. Endotoxin and Mediators. Meeting of Amsterdam June 1990 (Abstract).

  19. Teng, N. N. H., Kaplan, H. S., Hebert, J. M., Moore, C., Douglas, H., Wunderlich A, Braude, A. I. Protection against gram-negative bacteremia and endotoxemia with human monoclonal IgM antibodies. Proc. Natl. Acad. Sci. USA 82 (1985) 1790–1794.

    Google Scholar 

  20. Ziegler, E.: Use of anti-LPS antibodies to treat gram-negative sepsis. Endotoxin and Mediators. Meeting of Amsterdam June 1990 (Abstract).

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Marger, W. The last round against bacterial infections?. Infection 18, 197–199 (1990). https://doi.org/10.1007/BF01643384

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