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An improved specific IgM antibody assay for Epstein-Barr virus

Ein verbesserter Nachweis für spezifische Epstein-Barr-IgM-Antikörper

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Summary

A new method for detecting specific IgM antibodies to the Epstein-Barr virus using indirect fluorescence is presented. The procedure is simple and reproducible, and of great value for the diagnosis of an acute infection. The number of positive cells is higher than in the Epstein-Barr IgG test. It would seem that it is possible to detect a positive IgM-specific antigen with this new test.

Zusammenfassung

Berich über eine neue Immunofluoreszenz-Methode zur Erfassung spezifischer IgM-Epstein-Barr-Virus-Antikörper. Das Verfahren ist einfach und zuverlässig und für die Beurteilung einer akuten Infektion von großer Bedeutung. Die Zahl der positiven Zellen ist größer als im EBV-IgG-Test. Möglicherweise gelingt es, mit diesem neuen Test ein spezifisches IgM-Antigen nachzuweisen.

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Literature

  1. Schmitz, H., Scherer, M. IgM antibodies to Epstein-Barr virus in infectious mononucleosis. Arch. ges. Virusforsch. 37 (1972) 332.

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  2. Nikoskelainen, J., Leikola, J., Klemola, E. IgM Antibodies specific for Epstein-Barr virus in infectious mononucleosis without heterophil antibodies. Brit. med. J. 12 (1974) 72.

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Authors and Affiliations

  1. University Children's Hospital, Lindwurmstraße 4, D-8, Munich 2

    O. Goetz &  P. Peller

Authors
  1. O. Goetz
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  2. P. Peller
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Additional information

Study conducted with the support of the Friedrich-Baur-Stiftung, Munich.

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Goetz, O., Peller, P. An improved specific IgM antibody assay for Epstein-Barr virus. Infection 3, 229–230 (1975). https://doi.org/10.1007/BF01642771

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  • DOI: https://doi.org/10.1007/BF01642771

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