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Newer β-lactam antibiotics

Deutsche Kurzfassung am Schluß der Übersicht

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References

  1. Williams, J. D., Geddes, A. M. Advertising of antibiotics. Brit. Med. J. 2 (1973) 116.

    Google Scholar 

  2. Garrod, L. P. Advertising of antibiotics. Brit. Med. J. 2 (1973) 239.

    Google Scholar 

  3. Sutherland, R., Croydon, E. A. P., Rolinson, G. N. Amoxycillin: A new semi-synthetic penicillin. Brit Med. J. 3 (1972) 13–16.

    Google Scholar 

  4. Daehne, W. v., Frederiksen, E., Gundersen, E., Lund, F., Mørch, P., Petersen, H. J., Roholt, K., Tybring, L., Godtfredsen, W. O. Acyloxymethyl esters of ampicillin. J. Med. Chem. 13 (1970) 607–612.

    Google Scholar 

  5. Daehne, W. v., Godtfredsen, W. O., Rohold, K., Tybring, L. Pivampicillin, a new orally active ampicillin ester. Antimicrob. Ag. Chemother. 1970 (1971) 431–437.

    Google Scholar 

  6. Hamilton-Miller, J. M. T. Chemical manipulations of the penicillin nucleus: a review. Chemotherapia 12 (1967) 73–88.

    Google Scholar 

  7. Danø, P., From Hansen, P. Antibiotic treatment with pivampicillin chloride in respiratory and urinary tract infections. Chemotherapy 18 (1973) 63–71.

    Google Scholar 

  8. Brumfitt, W., Franklin, I., Hayek, L., Pursell, R. Treatment of urinary tract infection with pivampicillin. A new ampicillin derivative. Scand. J. Infect. Dis. 5 (1973) 59–65.

    Google Scholar 

  9. Marget, W., Daschner, F., Unertl, K. Investigations on pivampicillin in treatment in newborns and infants. Infection 1 (1973) 41–45.

    Google Scholar 

  10. Knothe, H., Lembke, U. Der Einfluß von ampicillin und pivampicillin auf die Darmflora des Menschen. Zbl. Bakt. Hyg., I. Abt. Orig. A 223 (1973) 324–332.

    Google Scholar 

  11. Binderup, E., Godtfredsen, W. O., Roholt, K. Orally active cephaloglycin esters. J. Antibiot. 24 (1971) 767 to 773.

    Google Scholar 

  12. Wallace, J. F., Atlas, E., Bear, D. M., Brown, N. K., Clark, H., Turck, M. Evaluation of an indanyl ester of carbenicillin. Antimicrob. Ag. Chemother. 1970 (1971) 223–226.

    Google Scholar 

  13. Butler, K. Metabolism and laboratory studies with indanyl-carbenicillin. Delaware State Medical Journal 43 (1971) 366–375.

    Google Scholar 

  14. English, A. R., Retsema, J. A., Ray, V. A., Lynch, J. E. Carbenicillin indanyl sodium, an orally active derivative of carbenicillin. Antimicrob. Ag. Chemother. 1 (1972) 185–191.

    Google Scholar 

  15. Taylor, W. A., Holloway, W. J. Clinical experience with oral carbenicillin. Delaware State Medical Journal 43 (1971) 381–383.

    Google Scholar 

  16. Symposium on oral indanyl carbencillin in the treatment of urinary tract infection. J. infect. Dis. Supplement 127 (1973) 97–167.

    Google Scholar 

  17. Leading article: An oral carbenicillin. Brit. Med. J. 3 (1973) 555–556.

    Google Scholar 

  18. Hardcastle, G. A., Johnson, D. A., Panetta, C. A., Scott, A. I., Sutherland, G. A. The preparation and structure of hetacillin. J. Org. Chem. 31 (1966) 897–899.

    Google Scholar 

  19. Sutherland, R., Robinson, O. P. W. Laboratory and pharmacological studies in man with hetacillin. Brit. Med. J. ii (1967) 804–808.

    Google Scholar 

  20. Smith, J. T., Hamilton-Miller, J. M. T. Hetacillin: a chemical and biological comparison with ampicillin. Chemotherapy 15 (1970) 366–378.

    Google Scholar 

  21. Schwartz, M. A., Hayton, W. L. Relative stability of hetacillin and ampicillin in solution. J. Pharm. Sci. 61 (1972) 906–909.

    Google Scholar 

  22. Gottstein, W. J., Misco, P. F., Cheney, L. C. Conversion of hetacillin into cephalexin. J. Org. Chem. 37 (1972) 2765–2767.

    Google Scholar 

  23. Sutherland, R., Burnett, J., Rolinson, G. N. α-carboxy-3-thienylmethylpenicillin (BRL 2288), a new semísynthetic penicillin: In vitro evaluation. Antimicrob. Ag. Chemother. 1970 (1971) 390–395.

    Google Scholar 

  24. Neu, H. C., Winshell, E. B. Semisynthetic penicillin 6-(D[-]-α-Carboxy-3-thienylacetamido) penicillanic acid active against Pseudomonas in vitro. Appl. Microbiol. 21 (1971) 66–70.

    Google Scholar 

  25. Bodey, G. P., Deerhake, B. In vitro studies of α-carboxyl-3-thienylmethyl penicillin, a new semisynthetic penicillin. Appl. Microbiol. 21 (1971) 61–65.

    Google Scholar 

  26. Adler, J. L., Burke, J. P., Wilcox, C., Finland, M. Susceptibility of Proteus species and Pseudomonas aeruginosa to penicillins and cephalosporins. Antimicrob. Ag. Chemother. 1970 (1971) 63–67.

    Google Scholar 

  27. Sabath, L. D., Stumpf, L. L., Wallace, S. J., Finland, M. Susceptibility of Diplococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis to 23 antibiotics. Antimicrob. Ag. Chemother. 1970 (1971) 53–56.

    Google Scholar 

  28. Sutherland, R., Wise, P. J. α-carboxy-3-thienylmethylpenicillin (BRL 2288), a new semisynthetic penicillin: Absorption and excretion in man. Antimicrob. Ag. Chemother. 1970 (1971) 402–406.

    Google Scholar 

  29. Knudsen, E. T., Rolinson, G. N., Sutherland, R. Carbencillin: A new semisynthetic penicillin active against Pseudomonas pyocyanea. Brit. Med. J. 3 (1967) 75–78.

    Google Scholar 

  30. Klastersky, J., Daneau, D. Comparison between carbenicillin and a α-carboxyl-3-thienylmethyl penicillin (BRL 2288), a new semisynthetic penicillin active against Pseudomonas aeruginosa. Curr. Therap. Res. 14 (1972) 503–509.

    Google Scholar 

  31. Bodey, G. P., Rodriguez, V. Advances in the management of Pseudomonas aeruginosa infections in cancer patients. Europ. J. Cancer 9 (1973) 435–441.

    Google Scholar 

  32. Neu, H. C., Winshell, E. B. In vitro studies of a semisynthetic penicillin, 6-(D[-]-α-carboxy-3-thienylacetamido) penicillanic acid (BRL 2288), active against Pseudomonas. Antimicrob. Ag. Chemother. 1970 (1971) 385–389.

    Google Scholar 

  33. Kamiya, K., Wada, Y., Nomura, H., Nishikawa, M., Morimoto, S. Semisynthetic β-lactam antibiotics. IV. The X-Ray analysis of monopotassium α-sulfophenylacetade monohydrate. The configuration of the acyl side chain of α-sulfobenzylpenicillin. Chem. Pharm. Bull. 21 (1973) 1037–1041.

    Google Scholar 

  34. Tsuchiya, K., Oishi, T., Iwagishi, C., Iwahi, T. In vitro antibacterial activity of disodium α-sulfobenzylpenicillin. J. Antibiot. 24 (1971) 607–619.

    Google Scholar 

  35. Morimoto, S., Nomura, H., Fugono, T., Minami, I., Hori, M., Masuda, T. Semisynthetic β-lactam antibiotics. 2. Synthesis and properties of D- and L-α-sulfobenzylpenicillins. J. Med. Chem. 15 (1972) 1108–1111.

    Google Scholar 

  36. Bodey, G. P., Rodriguez, V. Preliminary studies of 6-(D-α-sulfoaminophenylacetamido) penicillanic acid (BLP 1462) in the treatment of Pseudomonas infections. Curr. Therap. Res. 12 (1970) 363–368.

    Google Scholar 

  37. Morimoto, S., Nomura, H., Fugono, T., Minami, I., Ishiguro, T., Masuda, T. Semisynthetic β-lactam antibiotics. III. Structure — activity relationships of α-sulfopenicillins. J. Antibiot. 26 (1973) 146–152.

    Google Scholar 

  38. Vlietinck, A., Roets, E., Claes, P., Janssen, G., Vanderhaeghe, H. Preparation of 6-epi-phenoxymethyl- and 6-epi-benzyl-penicillin. J. Chem. Soc. Perkin Trans. 1 (1973) 937–942.

    Google Scholar 

  39. Basch, H., Erickson, R., Gadebusch, H. Epicillin: In vitro laboratory studies. Inf. Immun. 4 (1971) 44–49.

    Google Scholar 

  40. Gadebusch, H., Miraglia, G., Pansy, F., Renz, K. Epicillin: Experimental chemotherapy, pharmacodynamics, and susceptibility testing. Inf. Immun. 4 (1971) 50–53.

    Google Scholar 

  41. Limson, B. M., Siasoco, R. E., Dial, F. P. The effect of combined sodium epicillin injection and orally administered epicillin in the treatment of acute infective illness. Med. J. Aust. 2 (1972) 1348–1351.

    Google Scholar 

  42. Gordon, R. C., Regamey, C., Kirby, W. M. M. Comparative clinical pharmacology of amoxicillin and ampicillin administered orally. Antimicrob. Ag. Chemother. 1 (1972) 504–507.

    Google Scholar 

  43. Kosmidis, J., Williams, J. D., Andrews, J., Goodall, J. A. D., Geddes, A. M. Amoxycillin — pharmacology, bacteriology and clinical studies. Brit. J. clin. Prac. 26 (1972) 341–346.

    Google Scholar 

  44. Handsfield, H. H., Clark, H., Wallace, J. F., King, K. H., Turck, M. Amoxicillin, a new penicillin antibiotic. Antimicrob. Ag. Chemother. 3 (1973) 262–265.

    Google Scholar 

  45. May, J. R., Ingold, A. Amoxycillin in the treatment of chronic nontuberculous bronchial infections. Brit. J. Dis. Chest 66 (1972) 185–191.

    Google Scholar 

  46. Clinical evaluation of amoxycillin (BRL 2333): Chemotherapy 18 (1973) Supplement 1–114.

  47. Sjoberg, B., Ekstrom, B., Forsgren, U. α-azidopenicillin. 1 Chemistry, bacteriology and experimental chemotherapy. Antimicrob. Ag.t Chemother. 1967 (1968) 560–567.

    Google Scholar 

  48. Hansson, E., Magni, L., Wahlquist, S. α-azidopenicillin. 2 Preliminary clinical pharmacology. Antimicrob. Ag. Chemother. 1967 (1968) 568–572.

    Google Scholar 

  49. Tunevall, G., Frisk, A. R. Azidopenicillin, a new penicillin. Antimicrob. Ag. Chemother. 1967 (1968) 573 to 577.

    Google Scholar 

  50. Lund, F., Tybring, L. 6β-amidinopenicillanic acids — a new group of antibiotics. Nature New Biology 236 (1972) 135–137.

    Google Scholar 

  51. Greenwood, D., O'Grady, F. FL-1060: a new β-lactam antibiotic with novel properties. J. clin. Path. 26 (1973) 1–6.

    Google Scholar 

  52. Park, J. T., Burman, L. FL-1060: a new penicillin with a unique mode of action. Biochem. biophys. Res. comm. 51 (1973) 863–868.

    Google Scholar 

  53. Melchior, N. H., Blom, J., Tybring, L., Birch-Andersen, A. Light and electron microscopy of the early response of Escherichia coli to a 6β-amidinopenicillanic acid (FL 1060). Act. path. microbiol. Scand. B 81 (1973) 393–407.

    Google Scholar 

  54. Greenwood, D.: Ph. D. Thesis, University of London, (1973).

  55. Axelrod, J., Meyer, B. R., Hirschman, S. Z. Cephapirin: In vitro antibacterial spectrum. Appl. Microbiol. 22 (1971) 904–908.

    Google Scholar 

  56. Gordon, R. C., Barrett, F. F., Clark, D. J., Yow, M. D. Laboratory and pharmacologic studies of BL-P-1322 (cephapirin sodium) in children. Curr. Therap. Res. 13 (1971) 398–406.

    Google Scholar 

  57. Chisholm, D. R., Leitner, F., Misiek, M., Wright, G. E., Price, K. E. Laboratory studies with a new cephalosporanic acid derivative, BLP 1322. Antimicrob. Ag. Chemother. 1969 (1970) 244–246.

    Google Scholar 

  58. Linton, A. L., Bailey, R. R., Turnbull, D. I. Relative nephrotoxicity of cephalosporin antibiotics in an animal model. Canadian Medical Association Journal 107 (1972) 414–416.

    Google Scholar 

  59. Lane, A.Z., Taggart, J. G., Iles, R. L. Relative incidence of phlebitis caused by continuous intravenous infusion of cephapirin and cephalothin. Antimicrob. Ag. Chemother. 2 (1972) 234–235.

    Google Scholar 

  60. Inagaki, J., Bodey, G. P. Phlebitis associated with cephalosporins: Cephapirin versus cephalothin. Curr. Therap. Res. 15 (1973) 37–43.

    Google Scholar 

  61. Carrizosa, J., Levison, M. E., Kaye, D. Double-blind controlled comparison of phlebitis produced by cephapirin and cephalothin. Antimicrob. Ag. Chemother. 3 (1973) 306–307.

    Google Scholar 

  62. Bodner, S. J., Koenig, M. G. Clinical and in vitro evaluation of cephapirin, a new parenteral cephalosporin. Amer. J. Med. Sci. 263 (1972) 43–51.

    Google Scholar 

  63. Axelrod, J., Meyers, B. R., Hirschman, S. Z. Cephapirin: pharmacology in normal human volunteers. J. clin. Pharm. 12 (1972) 84–88.

    Google Scholar 

  64. Dittert, L. W., Doluiso, J. T., Griffen, W. O., van Harken, D. R., Cabana, B. E.: Pharmacokinetic interpretation of cephapirin plasma levels in humans. Abs. 8th Int. Congr. Chemother. Athens 1973 A-167.

  65. Fillastre, J. P., Laumonier, R., Humbert, G., Dubois, D., Metayer, J., Delpech, A. Insuffisances rendes aigues apres administration de cephalotine et de gentamycine. Nouvelle Presse Medicale 2 (1973) 444.

    Google Scholar 

  66. Martin, W. J., Wellman, W. E. Clinically useful antimicrobial agents. Postgrad. Med. 42 (1967) 370–381.

    Google Scholar 

  67. Jameson, S., McHenry, M. C., van Ommen, R. A., Gavan, T. L., Vidt, D. G., Butler, D. A. Cephapirin: clinical, pharmacological and microbiological studies. Delaware State Journal of Medicine 43 (1971) 384–390.

    Google Scholar 

  68. Khan, A. J., Pryles, C. V. Clinical and pharmacological evaluation of cephapirin sodium (BL-P-1322) in infants and children (cephapirin in pediatric patients). Curr. Therap. Res. 15 (1973) 198–204.

    Google Scholar 

  69. Meyers, B. R., Hirschman, S. Z., Nicholas, P. Cephanone: In vitro antibacterial activity and pharmacology in normal human volunteers. Antimicrob. Ag. Chemother. 2 (1972) 250–254.

    Google Scholar 

  70. Neu, H. C., Winshell, E. B. In vitro studies of cephanone, a 3-heterocyclicthiomethyl cephalosporin derivative. J. Antibiot. 26 (1973) 153–156.

    Google Scholar 

  71. Wick, W. E., Preston, D. A. Biological properties of three 3-heterocyclicthiomethyl cephalosporin antibiotics. Antimicrob. Ag. Chemother. 1 (1972) 221–234.

    Google Scholar 

  72. Kirby, W. M. M., Regamey, C. Pharmacokinetics of cefazolin compared with four other cephalosporins. J. inf. Dis. 128 (1973) S 341–346.

    Google Scholar 

  73. Pursiano, T. A., Misiek, M., Leitner, F., Price, K. E. Effect of assay medium on the antibacterial activity of certain penicillins and cephalosporins. Antimicrob. Ag. Chemother. 3 (1973) 33–39.

    Google Scholar 

  74. Misiek, M., Pursiano, T. A., Leitner, F., Price, K. E. Microbiological properties of a new cephalosporin, BL-S 339: 7-(phenylacetimidoyl-aminoacetamido)-3-(2-methyl-1, 3, 4-thiadiazol-5-ylthiomethyl) ceph-3-em-4-carboxylic acid. Antimicrob. Ag. Chemother. 3 (1973) 40 to 48.

    Google Scholar 

  75. Miraglia, G. J., Renz, K. J., Gadebusch, H. H. Comparison of the chemotherapeutic and pharmacodynamic activities of cephadrine, cephalothin and cephaloridine in mice. Antimicrob. Ag. Chemother. 3 (1973) 270–273.

    Google Scholar 

  76. Harvengt, C., De Schepper, P., Lamy, F., Hansen, J. Cephradine absorption and excretion in fasting and nonfasting volunteers. J. Clin. Pharm. 13 (1973) 36–40.

    Google Scholar 

  77. Limson, B. M., Siasoco, R. E., Dial, F. P. A new cephalosporin derivative cephradine in the treatment of acute infective diseases. Curr. Therap. Res. 14 (1972) 101–106.

    Google Scholar 

  78. Linda, L. Cephradine in the treatment of intestinal infections caused by shigella or salmonella organisms. Curr. Therap. Res. 14 (1972) 496–502.

    Google Scholar 

  79. Klastersky, J., Daneau, D., Weerts, D. Cephradine. Antibacterial activity and clinical effectiveness. Chemotherapy 18 (1973) 191–204.

    Google Scholar 

  80. Cephradine: A summary of preclinical and clinical studies and clinical pharmacology. J. Irish Med. Ass. (suppl.) 66 (1973) 1–37.

    Google Scholar 

  81. Neiss, E. S. Cephradine — a summary of preclinical studies and pharmacology. J. Irish Med. Ass. (suppl.) 66 (1973) 1–12.

    Google Scholar 

  82. Gower, P. E., Dash, C. H.: Parenteral cephalexin: serum and urine levels in humans. Abs. 7th Int. Congr. Chemoth., Prague (1971) A-1/7.

  83. Russell, A. D. In vitro studies with Ciba 36278-Ba, a new cephalosporin derivative. Microbios 6 (1972) 221–230.

    Google Scholar 

  84. Isenberg, H. D., Painter, B. G., Sampson-Scherer, J., Siegel, M. Clinical laboratory study of cephacetrile and cephalothin against bacteria recently isolated from clinical specimens. Amer. J. Clin. Path. 59 (1973) 700–705.

    Google Scholar 

  85. Neu, H. C., Winshell, E. B. In vitro evaluation of cephacetrile, a new cephalosporin antibiotic. J. Antibiot. 25 (1972) 400–404.

    Google Scholar 

  86. Russell, A. D. Interaction of a new cephalosporin, 7-cyanacetamidocephalosporanic acid, with some Gramnegative and Gram-positiveβ-lactamase-producing bacteria. Antimicrob. Ag. Chemother. 2 (1972) 255–260.

    Google Scholar 

  87. O'Callaghan, C. H., Morris, A., Kirby, S. M., Shingler, A. H. Novel method for detection ofβ-lactamases by using a chromogenic cephalosporin substrate. Antimicrob. Ag. Chemother. 1 (1972) 283–288.

    Google Scholar 

  88. Brogard, J. M., Haegele, P., Dorner, M., Lavillaureix, J. Biliary excretion of a new semisynthetic cephalosporin, cephacetrile. Antimicrob. Ag. Chemother. 3 (1973) 19–23.

    Google Scholar 

  89. Malandain, H., Humbert, G., Fillastre, J.-P., Acar, J., Dubois, D., Leroy, J., Robert, M., Daufresne, M.-F. Administration parentérale d'une nouvelle céphalosporine chez les malades insuffisants rénaux chroniques. Étude de la demi-vie plasmatique de l'antibiotique en fonction de la clearance glomérulaire. Path.-Biol. 21 (1973) 233–239.

    Google Scholar 

  90. Hodges, G. R., Scholand, J. F., Perkins, R. L. Cephacetrile: Clinical evaluation in 27 patients. Antimicrob. Ag. Chemother. 3 (1973) 228–234.

    Google Scholar 

  91. Opitz, A.: The treatment of chronic kidney infections with the cephalosporin derivative CIBA 36278-Ba. Abs. 7th Int. Congr. Chemother. Prague, A-14/21.

  92. Whitmarsh, V. B., Wise, R., Reeves, D. S., Hepburn, P. R.: Clinical and pharmacological experience with CIBA 36278-Ba, a new cephalosporin. Abs. 8th Int. Congr. Chemother. Athens. (1973) A-149.

  93. Ponticelli, C., Zucchelli, P., Casucci, G., Cervellati, I., Dalla Rosa, C., Giro, G., Motolese, M.: Comparative multicentre trial of cephacetrile and ampicillin in treatment of urinary tract infections. Abs. 8th Int. Congr. Chemother. Athens. (1973) A-171.

  94. Nishida, M., Matsubara, T., Murakawa, T., Mine, Y., Yokota, Y., Kuwahara, S., Goto, S. In vitro andin vivo evaluation of cefazolin, a new cephalosporin C derivative. Antimicrob. Ag. Chemother. 1969 (1970) 236–243.

    Google Scholar 

  95. Phair, J. P., Carleton, J., Tan, J. S. Comparison of cefazolin, a new cephalosporin antibiotic, with cephalothin. Antimicrob. Ag. Chemother. 2 (1972) 329–330.

    Google Scholar 

  96. Nishida, M., Matsubara, T., Murakawa, T., Mine, T., Yokota, Y. Cefazolin, a new semisynthetic cephalosporin antibiotic III. Absorption, excretion and tissue distribution in parenteral administration. J. Antibiot. 23 (1970) 184–195.

    Google Scholar 

  97. Ries, K., Levison, M. E., Kaye, D. Clinical andin vitro evaluation of cefazolin, a new cephalosporin antibiotic. Antimicrob. Ag Chemother. 3 (1973) 168–174.

    Google Scholar 

  98. Hodges, G. R., Saslaw, S. Experiences with cefazolin: a new cephalosporin antibiotic. Amer. J. Med. Sci. 265 (1973) 23–32.

    Google Scholar 

  99. De Schepper, P., Harvengt, C., Vranckx, C., Boon, B., Lamy, F. Pharmacologic study of cefazolin in volunteers. J. Clin. Pharm. 13 (1973) 83–88.

    Google Scholar 

  100. Seiga, K., Minogawa, M., Miyoshi, K., Yamagi, K., Sugiyama, Y. Clinical studies with cefazolin, a new cephalosporin antibiotic, compared with cephaloridine. Japanese J. Antibiot. 25 (1972) 72–78.

    Google Scholar 

  101. Gold, J. A., McKee, J. J., Ziv, D. S. Experience with cefazolin: an overall summary of pharmacologic and clinical trials in man. J. inf. Dis. 128 (1973) 415–421.

    Google Scholar 

  102. Eykyn, S., Jenkins, C., King, A., Phillips, I. Antibacterial activity of cefamandole, a new cephalosporin antibiotic, compared with that of cephaloridine, cephalothin, and cephalexin. Antimicrob. Ag. Chemother. 3 (1973) 657–661.

    Google Scholar 

  103. Williams, J. D., Andrews, J. The sensitivity ofHaemophilus influenzae to antibiotics. Brit. med. J. (1974/I) 134–137.

    Google Scholar 

  104. Nagarajan, R., Boeck, L. D., Gorman, M., Hamill, R. L., Higgens, C. E., Hoehn, M. M., Stark, W. M., Whitney, J. G. β-lactam antibiotics fromStreptomyces. J. Amer. Chem. Soc. 93 (1971) 2308–2310.

    Google Scholar 

  105. Stapley, E. O., Jackson, M., Hernandez, S., Zimmerman, B., Currie, S. A., Mochales, S., Mata, J. M., Woodruff, H. B., Hendlin, D. Cephamycin, a new family ofβ-lactam antibiotics. I. Production by actinomycetes, includingStreptomyces lactamdurans sup. n. Antimicrob. Ag. Chemother. 2 (1972) 122–131.

    Google Scholar 

  106. Miller, A. K., Celozzi, E., Pelak, A., Stapley, O., Hendlin, D. Cephamycins, a new family ofβ-lactam antibiotics. III.In vitro studies. Antimicrob. Ag. Chemother. 2 (1972) 281–286.

    Google Scholar 

  107. Daoust, D. R., Onishi, H. R., Wallick, H., Hendlin, D., Stapley, E. O. Cephamycins, a new family ofβ-lactam antibiotics: Antibacterial activity and resistance toβ-lactamase degradation. Antimicrob. Ag. Chemother. 3 (1973) 254–261.

    Google Scholar 

  108. Karady, S., Pines, S. H., Weinstock, L. M., Roberts, F. E., Brenner, G. S., Hoinowski, A. M., Cheng, T. Y., Sletzinger, M. Semisynthetic cephalosporins via a novel acyl exchange reaction. J. Amer. Chem. Soc. 95 (1972) 1410–1411.

    Google Scholar 

  109. Kosmidis, J., Hamilton-Miller, J. M. T., Gilchrist, J. N. G., Kerry, D. W., Brumfitt, W. Cefoxitin, a new semi-synthetic cephamycin: anin vitro andin vivo comparison with cephalothin. Brit. med. J. 4 (1973) 653–655.

    Google Scholar 

  110. Hamilton-Miller, J. M. T., Kerry, D. W., Brumfitt, W. Anin vitro comparison of cefoxitin, a semi-synthetic cephamycin, with cephalothin. J. Antibiot. 27 (1974) 42–48.

    Google Scholar 

  111. Spitzer, W. A., Goodson, T., Smithey, R. J., Wright, I. G.: General method for the synthesis ofβ-lactam antibiotics substituteda to theβ-lactam carbonyl. Chem. Commun. (1972) 1138–1139.

  112. Cama, L. D., Leanza, W. J., Beattie, T. R., Christensen, B. G. Substituted penicillin and cephalosporin derivatives. I Stereospecific introduction of the C-6(7) methoxy group. J. Amer. Chem. Soc. 95 (1972) 1408–1410.

    Google Scholar 

  113. Ho, P. P. K., Towner, R. D., Indelicato, J. M., Spitzer, W. A., Hoppel, G. A. Biochemical and microbiological studies on 6-substituted penicillins. J. Antibiot. 25 (1972) 627–628.

    Google Scholar 

  114. Ho, P. P. K., Towner, R. D., Indelicato, J. M., Wilham, W. J., Spitzer, W. A, Koppel, G. A. Biochemical and microbiological studies on 7-methoxycephalosporins. J. Antibiot. 26 (1973) 313–314.

    Google Scholar 

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Hamilton-Miller, J., Brumfitt, W. Newer β-lactam antibiotics. Infection 2, 82–94 (1974). https://doi.org/10.1007/BF01642027

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