Summary
The clinical significance of infections due to methicillin-resistant Staphylococcus aureus in eighty-two patients is assessed. Serious infections occurred. Three patients with postoperative pneumonia died. Wound infections remained localized but some patients had a prolonged stay in hospital. Assessment of treatment with theβ-lactamase resistant penicillins in eight cases showed that clinical failure of treatment resulted, and colonization with methicillin-resistant Staph. aureus was not prevented. The frequency of methicillin-resistant Staph. aureus was not shown to be associated with penicillin usage in our hospitals.
Zusammenfassung
Die Bedeutung Methicillin (Oxacillin)-resistenter Staphylokokken bei Infektionen von 82 Patienten wird abgegrenzt. Es traten schwere Infektionen auf. Drei Patienten starben nach post-operativer Pneumonie. Wundinfektionen blieben zwar lokalisiert, bei manchen Patinten wurde die Entlassung jedoch verzögert. Bei der Beurteilung der Behandlung mit Penicillinase-festem Penicillin ergaben sich in acht Fällen Therapieversager, weil eine Besiedlung mit Methicillin-resistenten Staphylokokken nicht verhindert werden konnte. Die Häufigkeit von Methicillin-resistenten Staphylokokken war nicht mit dem Penicillinverbrauch im Krankenhaus korreliert.
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Hone, R., Keane, C. A clinical study of infections caused by methicillin-resistant Staphylococcus aureus. Infection 2, 213–217 (1974). https://doi.org/10.1007/BF01641465
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DOI: https://doi.org/10.1007/BF01641465