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Legionärskrankheit in Deutschland

Legionnaires' disease in Germany

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Zusammenfassung

Im Februar 1979 erkrankte in München ein 51jähriger Mann unter den Zeichen einer grippeartigen Symptomatik, woraus sich eine Pneumonie entwickelte. Der Patient verstarb am achten Krankheitstag unter hohem Fieber, einer Leukopenie und Agranulozytose an einem unbeeinflußbaren Kreislaufversagen. Aus dem Lungengewebe und den histologischen Schnitten konnten mit Immunfluoreszenz typische Stäbchen nachgewiesen werden, die für eine Legionella pneumophila-Infektion sprachen. Der Erreger wurde auf CYE-Agar aus dem Lungengewebe isoliert, es handelte sich um eineLegionella pneumophila Serogruppe I. Die Diagnose wurde vom CDC, Atlanta, bestätigt. Es handelt sich um die erste Isolierung dieses Erregers bei einer tödlich verlaufenden Erkrankung in Mitteleuropa.

Summary

In February 1979 a 51 year old man fell will in Munich, displaying symptoms of an influenza-like illness which developed into pneumonia. The patient died eight days later of circulatory collapse which failed to respond to treatment, accompanied by high temperature, leucopenia and agranulocytosis. Typical rods detected in the lung tissue and histological sections by immunofluorescence indicated the possibility of aLegionella pneumophila infection. The pathogen isolated from the lung tissue on CYE agar was identified asL. pneumophila, sero-group I. The diagnosis was confirmed by the CDC, Atlanta. This is the first time this organism has been isolated in Central Europe from a case with a fatal outcome.

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Literatur

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Holze, E., Ruckdeschel, G. Legionärskrankheit in Deutschland. Infection 7, 149 (1979). https://doi.org/10.1007/BF01641317

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  • DOI: https://doi.org/10.1007/BF01641317

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