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Treatment with a single daily dose of gentamicin in urinary tract infection in relation to the site of infection

Therapie mit einmaliger Tagesdosis von Gentamicin in Beziehung zur Lokalisierung der Harnwegsinfektion

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Summary

Twenty-three patients with various types of recurrent urinary tract infection were treated with a single daily dose of 160 mg gentamicin for eight to nine days. The treatment eliminated bacteriuria in 19 patients. Evaluation of the therapeutical results according to the site of infection showed elimination of bacteriuria in all patients with lower urinary tract infection. Thus a single daily dose of gentamicin can be recommended in recurrent lower urinary tract infection, and also in upper urinary tract infection not associated with a major impairment of renal function.

Zusammenfassung

Dreiundzwanzig Patienten mit verschiedenen klinischen Typen rezidivierender chronischer Harninfektion wurden mit einer täglichen Gabe von 160 mg Gentamicin behandelt. Diese acht bis neun Tage dauernde Therapie erzielte eine Heilung von Bakteriurie bei 19 Patienten. In Beziehung zu dem durch Lokalisationstests nachgewiesenen Infektionssitz verschwand Bakteriurie bei allen Patienten mit unteren Harnwegsinfekt. Die Gentamicin-Therapie mit einer täglichen Dosis eignet sich vor allem für rezidivierende, in den unteren Harnwegen lokalisierte Infekte als auch für Infekte der oberen Harnwege, die eine Störung der Nierenfunktion ohne wesentliche Nierenbeteiligung aufweisen.

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Prát, V., Bohuslav, V. & Hatala, M. Treatment with a single daily dose of gentamicin in urinary tract infection in relation to the site of infection. Infection 6, 29–31 (1978). https://doi.org/10.1007/BF01641088

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  • DOI: https://doi.org/10.1007/BF01641088

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