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Ventriculitis, aqueductal stenosis and hydrocephalus in neonatal meningitis: Diagnose and treatment

Ventriculitis, Stenose des Aquaeductus cerebri und Hydrocephalus bei neonataler Meningitis. Diagnose und Therapie

Summary

Five newborns are presented who had meningitis and developed aqueductal stenosis. The diagnosis of obstruction was made by ventriculography during the course of meningitis. A variety of therapeutic measures (use of intraventricular antibiotics, use of reliably diffusible antibiotics, drainage of ventricles) led to varying results. Protocols should be established to assess each modality or combination thereof to help reduce the extremely high morbidity and mortality of this disease.

Zusammenfassung

Es wird über fünf Neugeborene mit Meningitis berichtet, die eine Stenose des Aquaeductes cerebri entwickelten. Die Diagnose der Obstruktion wurde im Verlauf der Meningitis durch Ventrikulographie erhoben. Eine Vielzahl therapeutischer Maßnahmen (Anwendung intraventrikulärer sowie zuverlässig diffusionsfähiger Antibiotika, Ventrikeldränage) führte zu unterschiedlichen Ergebnissen. Zur Beurteilung jeder Behandlungsmodalität oder Kombinationstherapie sollten Protokolle erstellt werden, um zu einer Verringerung der extrem hohen Morbidität und Mortalität dieser Krankheit beizutragen.

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Kaul, S., D'Cruz, J., Glista, B. et al. Ventriculitis, aqueductal stenosis and hydrocephalus in neonatal meningitis: Diagnose and treatment. Infection 6, 8–11 (1978). https://doi.org/10.1007/BF01641083

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Keywords

  • Public Health
  • Internal Medicine
  • Infectious Disease
  • General Practice
  • Meningitis