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The prevalence of ay and ad subtypes of the hepatitis B surface antigen in Belgium

Vorkommen der Hepatitis-B-Oberflächenantigen-Subtypen ay und ad in Belgien

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Summary

Subtyping in various groups of persons positive for hepatitis B surface antigen gave the following results: Among asymptomatic blood donors (healthy carriers) subtypead was found in 20, subtypeay in 24. Among symptomatic patients with acute hepatitis Bad was found in 25,ay in 29. Among patients of an institution for the mentally retardedad was found in 9,ay in 23. Among patients of a geriatric institutionay was found in 9; among medical personnel of the same geriatric institutionay was found in 3 persons. Among symphilis patientsad was found in 6,ay in 29; and in patients of a dialysis centreay was found in 6. These data show that neither subtype is really dominant in Belgium.

Zusammenfassung

Die Bestimmung der Subtypen an verschiedenen Personengruppen mit positivem Hepatitis-B-Oberflächenantigen erbrachte folgende Ergebnisse: Unter asymptomatischen Blutspendern (gesunde Träger) wurde der Subtypad bei 20, der Subtypay bei 24 festgestellt. In einer Gruppe symptomatischer Patienten mit akuter Hepatitis B wurdead bei 25 unday bei 29 ermittelt. Patienten einer Anstalt für geistig Behinderte wiesenad in 9 Fällen unday in 23 Fällen auf. Unter den Patienten einer geriatrischen Klinik wurdeay bei 9 Personen festgestellt, desgleichen bei 3 Personen des ärztlichen Personal derselben geriatrischen Klinik. Bei syphilitischen Patienten wurdead in 6 Fällen unday in 29 Fällen ermittelt. Unter den Patienten eines Dialysezentrums fand sichay in 6 Fällen. Diese Ergebnisse zeigen, daß keiner der beiden Subtypen in Belgien wirlich dominiert.

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Literature

  1. Bancroft, W. H., Mundon, F. K., Russel, Ph. K. Detection of additional antigenic determinants of hepatitis B antigen. J. Immunol. 109 (1972) 842–848.

    Google Scholar 

  2. Le Bouvier, G. L. Subspecificities of the Australia antigen complex. Am. J. Dis. Child. 123 (1972) 420–424.

    Google Scholar 

  3. Levine, C., Blumberg, G. S. Additional specificities of Australia antigen and the possible identification of the hepatitis carriers. Nature 22 (1969) 195–196.

    Google Scholar 

  4. Soulier, J. P., Courouce-Pauty, A. M. New determinants of hepatitis B antigen (Au or HB antigen). Vox. Sang. 25 (1973) 212–234.

    Google Scholar 

  5. Courouce, A. M., Holland, P. V., Muller, J. Y., Soulier, J. P. HBs antigen subtypes, pp. 20–41. S. Karger, Basel 1976.

    Google Scholar 

  6. Prince, A. M. An antigen detected in the blood during the incubation period of serum hepatitis. Proc. Nat. Acad. Sci. 60 (1968) 814–821.

    Google Scholar 

  7. Brummelhuis, H. G. J. Onderzoek naar de aanwezigheid van het Au-antigeen (serum hepatitis, SH-antigeen) en antistoffen tegen het Au-antigeen in donors-en patiëntent sera. Ned. T. Geneesk. 115 (1971) 181–185.

    Google Scholar 

  8. Vranckx, R., Ghysels, G., Cole, J., Peetermans, M. Opsporen van het Au/SH antigeen en de overeenstemmende antistoffen by bloedgevers te Antwerpen. Arch. Belg. Med. Soc. 30 (1972) 270–278.

    Google Scholar 

  9. Campbell, D. H., Garvey, J. S., Cremer. N. E., Sussdorf, D. M. Methods in immunology, pp. 183–234. W. A. Benjamin Inc., New York 1970.

    Google Scholar 

  10. Frösner, G. G., Berg, P. A. Change in prevalent subtypes of HBsAg in acute hepatitis B infections and its implications. Dev. Biol. Standard. 30 (1975) 152–156.

    Google Scholar 

  11. Magnius, L., Berg, R., Bjorvatn, B., Svedmyr, A. Shift in viral strains of hepatitis B in Stockholm as reflected by subtypes of hepatitis B in Stockholm as reflected by subtypes of hepatitis B antigen. Scand. J. Infect Dis. 5 (1973) 81–83.

    Google Scholar 

  12. Prince, A. M., Bratman, B., Jass, D., Ikran, H. Specificity of the direct solid-phase radioimmunoassay for detection of hepatitis B antigen. Lancet 1 (1973) 1346–1950.

    Google Scholar 

  13. Adam, E., Hollinger, B., Melnick, J., Duenas, A., Rawls, W. Type B hepatitis antigen and antibody among prostitutes and nuns. J. Infect. Dis. 129 (1974) 317–321.

    Google Scholar 

  14. Szmuness, W., Prince, A. M., Hirsch, R. L., Bratman, B. Familial clustering of hepatitis B infection N. Engl. J. Med. 289 (1973) 1162–1166

    Google Scholar 

  15. Armitage, P. Statistical methods in medical research, pp. 101–131. Blackwell, Oxford 1971.

    Google Scholar 

  16. Frösner, G. G., Ziegler, G. B. Increasing prevalence of subtype y of HBsAg in Southwest Germany. N. Engl. J. Med. 293 (1975) 667.

    Google Scholar 

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Authors and Affiliations

  1. Institute of Hygiene and Epidemiology, Juliette Wytsmanstraat, 14, B-1050, Brussels, Belgium

    R. Vranckx

  2. Belgian Red Cross, Blood Transfusion Centre, Belgiëlei 34, B-2000, Antwerp, Belgium

    M. J. Cole

  3. Department of Haematology and Immunology, University of Antwerp, Universiteitsplein, B-2610, Wilrijk, Belgium

    M. Peetermans

Authors
  1. R. Vranckx
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  2. M. J. Cole
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  3. M. Peetermans
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Vranckx, R., Cole, M.J. & Peetermans, M. The prevalence of ay and ad subtypes of the hepatitis B surface antigen in Belgium. Infection 6, 2–4 (1978). https://doi.org/10.1007/BF01641081

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  • DOI: https://doi.org/10.1007/BF01641081

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