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Plasma testosterone in chronic human brucellosis

Plasmatestosteron bei chronischer Brucellose des Menschen

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Summary

Our studies were carried out in 25 male patients, aged 20 to 45 years, in whom the diagnosis of chronic brucellosis had been confirmed. Plasma testosterone levels were measured after five to seven days of sexual abstinence and after human choriogonadotropine stimulation. Testosterone was measured by radioimmunoassay. The basic plasma testosterone levels were 220–975 ng/100 ml. Response to human choriogonadotropine (HCG) stimulation was only achieved in six patients. The basic levels of plasma testosterone and levels after stimulation were closely related to changes in the testes and seminal fluid.

Zusammenfassung

25 männliche Patienten zwischen 20 und 45 Jahren mit der gesicherten Diagnose einer chronischen Brucellose wurden untersucht. Die Plasma-Testosteronspiegel wurden nach fünf- bis siebentägiger sexueller Abstinenz und nach Stimulation mit menschlichem Choriogonadotropin bestimmt. Die Testosteronbestimmung wurde mit einem Radioimmunoassay durchgeführt. Die Testosteronbasalspiegel betrugen 220–975 ng/100 ml. Nur sechs Patienten reagierten normal auf Stimulation mit menschlichem Choriogonadotropin (HCG). Die Plasma-Testosteronbasalspiegel und die Spiegel nach Stimulation standen in enger Korrelation zu den Veränderungen an den Testes und in der Samenflüssigkeit.

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Literature

  1. Kassur, B., Dziubek, Z. Andrologic studies and sexual potency in chronic human brucellosis. Infection 8 (1980) 94–97.

    Article  CAS  PubMed  Google Scholar 

  2. Stupnicki, R., Barcikowski, B., Kwiatkowska, Z. Oznaczanie testosteronu we krwi metoda radiokompetycyjna. Endokr. Pol. 22 (1971) 485–490.

    CAS  PubMed  Google Scholar 

  3. Pui-Yuen, W., Wood, D. E., Johnson, T. Routine radioimmunoassay of plasma testosterone and results for various endocrine disorders. Clin. Chem. 21 (1975) 206–210.

    Google Scholar 

  4. Fraiser, S. D., Gaffort, F., Horton, R. Plasma androgens in childhood and adolescence. J. Clin. Endocrin. Metab. 29 (1969) 1404–1408.

    Article  Google Scholar 

  5. Fairman, G. Venous testosterone levels. Lancet II (1973) 861.

    Article  Google Scholar 

  6. Lipsett, M. B. Steroid secretion by the testis in man. In:James, V. H. T., Serio, M., Martini, L. (eds.): The endocrine function of human testis. Vol. II. Academic Press, Inc., New York, London 1974, pp. 1–12.

    Chapter  Google Scholar 

  7. Jaffee, W. L., McCormack, W. M., Vaitukaitis, J. L. Plasma hormones and the sexual preferences of men. Psychoneuroendocrinology 5 (1980) 33–38.

    Article  CAS  PubMed  Google Scholar 

  8. Eik-Nes, K. B. Human chorionic gonadotrophin as stimulator for androgen secretion. In:James, V. H. T., Serio, M., Martini, L. (eds.): The endocrine function of the human testis. Vol. II. Academic Press, Inc., New York, London 1974, pp. 207–219.

    Chapter  Google Scholar 

  9. Scurry, M. T., Bruton, J., Berry, K. D. The effect of chorionic gonadotrophin on steroid excretion. Arch. Intern. Med. 128 (1971) 561–565.

    Article  CAS  PubMed  Google Scholar 

  10. Raboch, J., Starka, L.: Plasmatic testosterone in men with disturbances of somatosexual development. In:Dörner, G., Barth, J. A. (eds.): Endocrinology of sex. Leipzig 1974, pp. 140–145.

  11. Mahoudeall, J. A., Bricaire, H. La stimulation de la sécrétion testiculaire par la gonadotrophine chorionique. Résultats chez l'homme normal et chez les hypogonadiques. Nouv. Presse Méd. 5 (1976) 767–770.

    Google Scholar 

  12. Sachar, E. J., Halpern, F., Rosenfeld, R. S., Gallogher, T. F., Hellman, L. Plasma and urinary testosterone in depressed men. Arch. Gen. Psychiatry 28 (1973) 15–18.

    Article  CAS  PubMed  Google Scholar 

  13. Cooper, A. J., Ismail, A. A. A., Smith, C. G., Loraine, J. P. Androgen function in “psychogenic” and “constitutional” types of impotence. Br. Med. J. 3 (1970) 17–19.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Döcke, F. Neurohormonal regulation of male gonad function. Z. Gesamte Inn. Med. 34 (1979) 589–592.

    PubMed  Google Scholar 

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Dziubek, Z. Plasma testosterone in chronic human brucellosis. Infection 9, 167–169 (1981). https://doi.org/10.1007/BF01640972

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