Summary
Our studies were carried out in 25 male patients, aged 20 to 45 years, in whom the diagnosis of chronic brucellosis had been confirmed. Plasma testosterone levels were measured after five to seven days of sexual abstinence and after human choriogonadotropine stimulation. Testosterone was measured by radioimmunoassay. The basic plasma testosterone levels were 220–975 ng/100 ml. Response to human choriogonadotropine (HCG) stimulation was only achieved in six patients. The basic levels of plasma testosterone and levels after stimulation were closely related to changes in the testes and seminal fluid.
Zusammenfassung
25 männliche Patienten zwischen 20 und 45 Jahren mit der gesicherten Diagnose einer chronischen Brucellose wurden untersucht. Die Plasma-Testosteronspiegel wurden nach fünf- bis siebentägiger sexueller Abstinenz und nach Stimulation mit menschlichem Choriogonadotropin bestimmt. Die Testosteronbestimmung wurde mit einem Radioimmunoassay durchgeführt. Die Testosteronbasalspiegel betrugen 220–975 ng/100 ml. Nur sechs Patienten reagierten normal auf Stimulation mit menschlichem Choriogonadotropin (HCG). Die Plasma-Testosteronbasalspiegel und die Spiegel nach Stimulation standen in enger Korrelation zu den Veränderungen an den Testes und in der Samenflüssigkeit.
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Dziubek, Z. Plasma testosterone in chronic human brucellosis. Infection 9, 167–169 (1981). https://doi.org/10.1007/BF01640972
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DOI: https://doi.org/10.1007/BF01640972