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Infectious complications of burns casualties during the yom-kippur war

Infektiöse Komplikationen von Verbrennungen während des Yom-Kippur-Krieges

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Summary

During the October 1973 military conflict, 41 burned patients hospitalized at the Sheba Medical Center were closely followed up. All the patients who had burns occupying 20% or more of the body surface developed wound infections. Pseudomonas aeruginosa was the major pathogen isolated. Most infections occurred during the second week following the injury. Serial cultures revealed that only the isolation of Proteus species and P. aeruginosa from wounds could predict an infection caused by those microorganisms. During treatment with gentamicin and carbenicillin a marked increase in carbenicillin-resistant P. acruginosa and gentamicin-resistant Klebsiella strains was noted. Cross-infection with carbenicillin-resistant P. aeruginosa was not a major cause in the development of resistant strains.

Zusammenfassung

Während des Yom-Kippur-Krieges wurden die Krankheitsverläufe von 41 Patienten mit Verbrennungen im Sheba Medical Center genau erfaßt. Alle Patienten, die Verbrennungen von 20% oder mehr der Hautoberfläche aufwiesen, entwickelten Wundinfektionen. Der am häufigsten isolierte Erreger war Pseudomonas acruginosa. Die meisten Infektionen traten während der zweiten Woche nach der Verbrennung auf. Verlaufskulturen bewiesen an Hand der alleinigen Isolierung von Proteus-Spezies und P. aeruginosa, daß eine Infektion durch diese Keime zustande kam. Während der Behandlung mit Gentamicin und Carbencillin trat ein deutlicher Anstieg von Carbencillin-resistenten P. aeruginosa und Gentamicin-resistenten Klebsiella-Stämmen auf. Die Übertragung von Carbencillin-resistenten P. aeruginosa im Hospital war nicht in erster Linie für das Auftreten der resistenten Stämme verantwortlich.

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Literature

  1. Alexander, J. W. Control of infection following burn injury. Arch. Surg. 103 (1971) 435–441.

    Google Scholar 

  2. Baxter, C. R., Curreri, R. W., Marvin, J. A. Control of burn wound sepsis. Surg. Clin. N. Amer. 53 (1973) 1509–1518.

    Google Scholar 

  3. Bruck, H. M., Nash, G., Stein, J. M., Lindberg, R. B. Studies on the occurrence and significance of yeasts and fungi in the burn wound. Ann. Surg. 176 (1972) 108–110.

    Google Scholar 

  4. Cox, C. E. Gentamicin. Med. Clin. N. Amer. 54 (1970) 1305–1315.

    Google Scholar 

  5. Duncan, I. B. R. Susceptibility of 1500 isolates of Pseudomonas aeruginosa to gentamicin, carbenicillin, colistin and polymixin B. Antimicrob. Ag. Chemoth. 5 (1974) 9–15.

    Google Scholar 

  6. Foley, F. D., Moncrief, J. A., Mason, A. D. Pathology of the lung in the fatally burned patients. Ann. Surg. 167 (1968) 251–264.

    Google Scholar 

  7. Foley, F. D. The burn autopsy: Fatal Complications of burns. Amer. J. Clin. Pathol. 52 (1969) 1–13.

    Google Scholar 

  8. Fullbrock, P. D., Elson, S. W., Slocombe, B. R-factor mediatedβ-lactamase in Pseudomonas aeruginosa. Nature 226 (1970) 1054–1056.

    Google Scholar 

  9. Greene, W. H., Moody, M., Schimpff, S., Young, V. M., Wiernik, P. H. Pseudomonas aeruginosa resistant to carbenicillin and gentamicin. Ann. Int. Med. 79 (1973) 684–689.

    Google Scholar 

  10. Hoffman, T. A., Bullock, W. E. Carbenicillin therapy of Pseudomonas and other gram negative bacillary infections. Ann. Int. Med. 73 (1970) 165–171.

    Google Scholar 

  11. Holmes, R. K., Minshew, B. H., Gould, K., Sanford, J. P. Resistance of Pseudomonas aeruginosa to gentamicin and related aminoglycoside antibiotics. Antimicrob. Ag. Chemother. 6 (1974) 253–257.

    Google Scholar 

  12. Jones, R. J., Jackson, D. M. G., Lowbury, E. J. L. Antiserum and antibiotics in the prophylaxis of burns against Pseudomonas aeruginosa. Brit. J. Plast. Surg. 19 (1968) 43–57.

    Google Scholar 

  13. Jones, R. J., Lowbury, E. J. L. Prophylaxis and therapy for Pseudomonas aeruginosa infection with carbenicillin and with gentamicin. Brit. med. J. 3 (1967) 79–82.

    Google Scholar 

  14. Kefalides, N. A., Arana, J. A., Bazan, A., Velarde, N., Rosenthal, S. M. Evaluation of antibiotic prophylaxis and gamma globulin, plasma albumin and saline solution therapy in severe burns. Ann. Surg. 159 (1964) 496–506.

    Google Scholar 

  15. Lowbury, E. J. L., Lilly, H. A., Kidson, A., Ayliffe, G. A. J. Sensitivity of Pseudomonas aeruginosa to antibiotics: Emergence of strains highly resistant to carbenicillin. Lancet (1969/II) 448–452.

    Google Scholar 

  16. Lowbury, E. J. L. Infection associated with burns. Postgrad. Med. J. 48 (1972) 338–343.

    Google Scholar 

  17. Lowbury, E. J. L., Rabb, J. R., Roe, E. Clearance from a hospital of gram negative bacilli that transfer carbenicillin resistance to Pseudomonas aeruginosa. Lancet (1972/II) 941–945.

    Google Scholar 

  18. Marks, M. I., Eickhoff, T. C. Carbenicillin: A clinical and laboratory evaluation. Ann. Int. Med. 73 (1970) 179–187.

    Google Scholar 

  19. Moncrief, J. A. Burns. N. Eng. J. Med. 288 (1973) 444–454.

    Google Scholar 

  20. Pruitt, B. A., Divincenti, F. C., Mason, A. D., Foley, F. D., Flemma, R. J. The occurrence and significance of pneumonia and other pulmonary complications in burned patients: Comparison of conventional and typical treatment. J. Trauma 10 (1970) 519–531.

    Google Scholar 

  21. Pruitt, B. A. Infections caused by Pseudomonas species in patients with burns and in other surgical patients. J. Inf. Dis. 130 (1974) Suppl. 58–66.

    Google Scholar 

  22. Roe, E., Jones, R. J., Lowbury, E. J. L. Transfer of antibiotic resistance between Pseudomonas aeruginosa, E. coli and gram negative bacilli in burns. Lancet (1972/I) 149.

    Google Scholar 

  23. Shuck, J. M. Infection control in burns: Topical and systemic. Surg. Clin. N. Amer. 52 (1972) 1425–1438.

    Google Scholar 

  24. Simchen, E., Sachs, T. Infection in war wounds. Experience during the 1973 October war in Israel. Ann. Surg. 182 (1975) 754–761.

    Google Scholar 

  25. Stone, H. H., Kolb, L. D. The evaluation and spread of gentamicin resistant Pseudomonas. J. Trauma 11 (1971) 586–589.

    Google Scholar 

  26. Wickman, K. Studies on burns' bacteriology. Acta Chir. Scand. Suppl. 408 (1970) 1–34.

    Google Scholar 

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Sidi, Y., Bogokowski, B., Tsur, H. et al. Infectious complications of burns casualties during the yom-kippur war. Infection 5, 214–218 (1977). https://doi.org/10.1007/BF01640783

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