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Klinische Erfahrungen bei der Behandlung schwerer Infektionen mit Cefotaxim

Clinical experience in the treatment of severe infections with cefotaxime

  • Innere Medizin/Intensivmedizin
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Zusammenfassung

Mit dem neuen halbsynthetischen Cephalosporin Cefotaxim wurden 20 Patienten der internistischen und chirurgischen Klinik behandelt. Das Alter der zwölf weiblichen und acht männlichen Patienten lag zwischen 16 und 73 Jahren. Sie litten an teils schweren Grunderkrankungen. Die Dosierung schwankte zwischen 2 und 12 g/Tag. Im Mittel lag sie bei 4 g. In zehn Fällen konnte eine Heilung erzielt werden, in sieben Fällen trat eine klinische Besserung ein. Bei vier Patienten kam es zu einer Superinfektion mitCandida albicans. Die allgemeine Verträglichkeit von Cefotaxim war gut, schwere Nebenwirkungen konnten nicht beobachtet werden.

Summary

Twenty patients in the medical and surgical departments were treated with the new semisynthetic cephalosporin cefotaxime. The twelve female and eight male patients were aged between 16 and 73 years. They were suffering from underlying illnesses which in some cases were severe. In ten patients the infection was cured, in seven patients there was clinical improvement. Superinfection withCandida albicans occurred in four patients. Cefotaxime was generally well-tolerated, and no serious side-effects were observed.

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Krüger, E., Fischer, M., Schleicher, P. et al. Klinische Erfahrungen bei der Behandlung schwerer Infektionen mit Cefotaxim. Infection 8 (Suppl 4), S462–S465 (1980). https://doi.org/10.1007/BF01639422

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  • DOI: https://doi.org/10.1007/BF01639422

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