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Pseudomonas infections

Pseudomonas-Infektionen

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Summary

Infections caused byPseudomonas aeruginosa are of increasing importance and are common causes of death. The organism is widely disseminated in hospitals, flourishing in warm, moist environments such as intensive care and neonatal units. It is a common contaminante of medical and surgical equipment.P. aeruginosa is resistant to most antibiotics and only sensitive to a relatively small number of agents. However, resistance is now developing to some of these.P. aeruginosa very rarely causes infections in healthy subjects. It is usually an opportunist pathogen producing disease in patients with compromised host defence mechanisms. Infections caused byP. aeruginosa are frequently associated with extensive tissue destruction. This paper discusses some aspects of pathogenesis, treatment and prevention ofPseudomonas infections.

Zusammenfassung

Infektionen durchPseudomonas aeruginosa nehmen an Bedeutung zu; sie sind eine häufige Todesursache. Der Erreger ist in Krankenhäusern weit verbreitet und gedeiht in warmer, feuchter Umgebung, wie beispielsweise auf Intensiv- und Neugeborenenstationen. Er kontaminiert häufig intern-medizinisch und chirurgisch angewandte Geräte.Pseudomonas aeruginosa ist gegenüber den meisten Antibiotika resistent und nur gegenüber einer geringen Anzahl von Substanzen empfindlich. Doch entwickelt sich nun auch gegenüber einigen von diesen Substanzen eine Resistenz.P. aeruginosa verursacht bei gesunden Personen nur sehr selten Infektionen. Er ist ein opportunistischer Keim, der bei Patienten mit gestörten Abwehrmechanismen Krankheiten hervorruft. Infektionen durchP. aeruginosa sind häufig mit ausgedehnten Gewebedestruktionen verbunden. In der vorliegenden Arbeit werden einige Gesichtspunkte der Pathogenese, der Behandlung und Prävention vonPseudomonas-Infektionen diskutiert.

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Literature

  1. Keys, T. F., Washington, J. A. Gentamicin — resistantPseudomonas aeruginosa — Mayo Clinic experience, 1970–76. Mayo Clin. Proc. 52 (1977) 797–801.

    Google Scholar 

  2. Bridges, K., Kidson, A., Lowbury, E. J. L., Wilkins, M. D. Gentamicin — and silver — resistant Pseudomonas in a Burns Unit. Br. Med. J. 1 (1979) 446–449.

    Google Scholar 

  3. Kazmierowski, J. A., Reynolds, H. Y., Kauffman, J. C., Durbin, W. A., Graw, R. G., Devin, H. B. Experimental pneumonia due toPseudomonas aeruginosa in leukopenic dogs: Prolongation of survival by combined treatment with passive antibody to Pseudomonas and granulocyte transfusions. J. Infect. Dis. 135 (1977) 438–442.

    Google Scholar 

  4. Baltch, A. L., Griffin, P. E. Pseudomonas aeruginosa bacteraemia: a clinical study of 75 patients. Am. J. Med. Sci. 274 (1977) 119–129.

    Google Scholar 

  5. Winston, D. J., Gale, R. P., Meyer, D. V., Young, L. S. Infectious complications of human bone marrow transplantation. Medicine (Baltimore) 58 (1979) 1–31.

    Google Scholar 

  6. Schimpff, S. C., Green, W. H., Young, V. M., Wiernick, P. H. Significance ofPseudomonas aeruginosa in the patient with leukaemia or lymphoma. J. Infect. Dis. 130 (1974) 24–32.

    Google Scholar 

  7. Reyes, M. P., Pulutke, W. A., Wylin, R. F., Larner, A. M. Pseudomonas endocarditis in Detroit Medical Centre 1969–1972. Medicine (Baltimore) 52 (1973) 173–194.

    Google Scholar 

  8. Pickering, L. K., Ericsson, C. D., Guillermo, R. P., Blevins, J., Miner, M. E. Intraventricular and parenteral gentamicin therapy for ventriculitis in children. Am. J. Dis. Child. 132 (1978) 480–483.

    Google Scholar 

  9. Ayliffe, G. A. J., Barry, D. R., Lowbury, E. J. L., Roper-Hall, M. J., Walker, W. M. Post-operative infection withPseudomonas aeruginosa in an eye hospital. Lancet I (1966) 1113.

    Google Scholar 

  10. Alcock, S. R. Acute otitis externa in divers working in the North Sea: A microbiological survey of seven saturation dives. J. Hyg. Cambridge 78 (1977) 395–409.

    Google Scholar 

  11. Zaky, D. A., Bentley, D. W., Lowy, K., Betts, R. F., Douglas, R. G. Malignant external otitis: Severe form of otitis in diabetic patients. Am. J. Med. 61 (1976) 298–302.

    Google Scholar 

  12. Jones, R. J., Roe, E. A., Gupta., J. L. Controlled trials of a polyvalent Pseudomonas vaccine in burns. Lancet II (1979) 977–982.

    Google Scholar 

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Geddes, A.M. Pseudomonas infections. Infection 8, 242–244 (1980). https://doi.org/10.1007/BF01639045

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  • DOI: https://doi.org/10.1007/BF01639045

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