Summary
A total of 30 urinary bladder cytological specimens (urine and bladder washings) from 25 patients were reacted with a panel of 8 monoclonal antibodies predominantly derived from urinary bladder carcinoma, using avidin-biotin complex (ABC) immunohistochemical methodology. The clinical and epidemiological history of each of the patients evaluated was also revewed. A relatively high degree of sensitivity and specificity in the detection of malignancy was obtained in tests of urinary bladder cytological specimens with a combination of monoclonal antibodies. A role for monoclonal antibodies in the diagnosis of urinary bladder cytological specimens is discussed.
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Panosian, K.J.M., Lopez-Beltran, A., Croghan, G.A. et al. An immunohistochemical evaluation of urinary bladder cytology using monoclonal antibodies. World J Urol 7, 173–177 (1989). https://doi.org/10.1007/BF01637379
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DOI: https://doi.org/10.1007/BF01637379