Zusammenfassung
Mit Hilfe zytochemischer Untersuchungen kann bei der Haarzell-Leukämie ein Polymorphismus der sauren Phosphatase (SP) nachgewiesen werden. In einem von vier untersuchten Fällen fehlt jegliche SP in den Haarzellen, bei zweien ist nur tartratsensible SP nachweisbar, im vierten tartratresistente SP in hoher Aktivität. Nach unseren Erfahrungen spricht das Fehlen tartratresistenter SP nicht gegen die Diagnose Haarzell-Leukämie.
Summary
In four cases of hairy cell leukemia a cytochemical polymorphism concerning acid phosphatase (AP) is evident. Any AP is lacking in all hairy cells of one case; only tartrate inhibitable AP is occurring in two cases; in another case tartrate resistant AP is found in high activity. Thus, the lack of tartrate resistant AP seems not to be an argument against hairy cell leukemia.
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Schaefer, HE., Hellriegel, KP., Zach, J. et al. Zytochemischer Polymorphismus der sauren Phosphatase bei Haarzell-Leukämie. Blut 31, 365–370 (1975). https://doi.org/10.1007/BF01634003
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DOI: https://doi.org/10.1007/BF01634003