Skip to main content
Log in

Zum Verhalten des Erythropoetins bei aregeneratorischen Blutbildungsstörungen unter Therapie mit anabolen Steroiden

  • Originalarbeiten
  • Published:
Blut: Zeitschrift für die Gesamte Blutforschung Aims and scope Submit manuscript

Zusammenfassung

Die von anderen Autoren festgestellten Erhöhungen des Serum-Erythropoetin-Spiegels bei Behandlung verschiedener Anämieformen mit Testosteron oder Fluoxymesteron konnten bei der Behandlung 8 anämischer Patienten mit Mesterolon oder Oxymetholon nicht bestätigt werden.

Summary

The increased levels of serum-erythropoietin which were reported by several authors in various forms of anemias treated with testosterone or fluoxymesterone could not be found in 8 anemic patients treated with mesterolone or oxymetholone.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Literatur

  1. Alexanian, R.: Urinary excretion of erythropoitin in normal men and women. Blood28, 344 (1966).

    CAS  PubMed  Google Scholar 

  2. Alexanian, R.: Erythropoietin and erythropoiesis in anemic men following androgens. Blood33, 564 (1969).

    CAS  PubMed  Google Scholar 

  3. Allen, D. M., M. H. Fines, T. F. Necheles and W. Dameshek: Oxymetholone therapy in aplastic anemia. Blood32, 83 (1968).

    CAS  PubMed  Google Scholar 

  4. Björntorp, P., A. Weinfeld and P. Lundin: A case of aplastic anemia successfully treated with androgens. Acta Med. Scand.177, 275 (1965).

    Google Scholar 

  5. Duarte, L., L. S. Medal, J. Labardini and L. Arriaga: The erythropoietic effects of anabolic steroids. Proc. Soc. Exper. Biol. Med.125, 1030 (1967).

    Article  CAS  Google Scholar 

  6. Fried, W., R. De Gowin and C. W. Gurney: Erythropoietin effect of testosterone in polycytaemic mice. Proc. Soc. Exp. Biol. Med.117, 839 (1964).

    Article  CAS  PubMed  Google Scholar 

  7. Gardner, F. H. and J. C. Pringle: Androgens and erythropoiesis. I. Preliminary clinical observations. Arch. Int. Med.107, 846 (1961).

    Article  CAS  Google Scholar 

  8. Gardner, F. H. and J. C. Pringle: Androgens and erythropoiesis. II. Treatment of myeloid metaplasia. New. Engl. J. Med.264, 103 (1961).

    Article  CAS  PubMed  Google Scholar 

  9. Gardner, H. and D. G. Nathan: Androgens and erythropoiesis. III. Further evaluation of testosterone treatment of myelofibrosis. New. Engl. J. Med.274, 420 (1966).

    Article  CAS  PubMed  Google Scholar 

  10. Gardner, F. H., D. G. Nathan, S. Piomelle and J. F. Cummins: The erythraemic effect of androgens. Brit. J. Haemat.14, 611 (1968).

    Article  CAS  PubMed  Google Scholar 

  11. Gurney, C. W. and W. Fried: Further studies on the erythropoietic effect of androgens. J. Lab. Clin. Med.65, 775 (1965).

    CAS  PubMed  Google Scholar 

  12. Kennedy, B. J.: Androgenic hormone therapy in lymphatic leukemia. J. A. M. A.190, 1130 (1964).

    Article  CAS  PubMed  Google Scholar 

  13. Kennedy, B. J.: Stimulation of haematopoiesis by androgenic hormones. Geriatrics20, 808 (1965).

    CAS  PubMed  Google Scholar 

  14. Mirand, E. A., A. S. Gordon and J. Wenig: Mechanism of testosterone action in erythropoiesis. Nature206, 290 (1965).

    Article  Google Scholar 

  15. Moores, R. R., C. S. Wright, L. R. Collins, E. Gardner, J. P. Lewis and L. L. Smith: Stimulation of erythropoietin by androgen in the human. Scand. J. Haemat.5, 415 (1968).

    Article  CAS  PubMed  Google Scholar 

  16. Naets, J. P. and M. Wittek: Mechanism of action of androgens on erythropoiesis. Amer. J. Physiol.210/2, 315 (1966).

    Google Scholar 

  17. Najean, Y., C. Dresch, G. Schaison, J. Chassigneux, C. Jacquillat and J. Bernard: Etude de l'effet de l'androgenothérapie au cours des insuffisances médullaires. La presse medicale74, 2537, (1966).

    CAS  PubMed  Google Scholar 

  18. Rishpon-Meyerstein, N., T. Kilbridge, J. Simone and W. Fried: The effect of testosterone on erythropoinetin. Blood31, 453 (1968).

    CAS  PubMed  Google Scholar 

  19. Sanchez-Medal, L., A. Gomez-Leal and L. Duarte-Zapata: Anabolic therapy in aplastic anemia (Summary). Blood28, 979 (1966).

    Google Scholar 

  20. Schmid, J. R., J. M. Kiely, G. L. Pease and M. M. Hargraves: Acquired pure red cell agenesis. Report of 16 cases and review of the literature. Acta haemat. Basel30, 255 (1963).

    Article  CAS  PubMed  Google Scholar 

  21. Shahidi, N. T. and L. K. Diamond: Testosterone induce remission in aplastic anemia. Amer. J. Dis. Ch.98, 293 (1959).

    CAS  Google Scholar 

  22. Shahidi, N. T. and L. K. Diamond: Testosterone induced remission in aplastic anemia of both acquired and congenital types. Further observations in 24 cases. New Engl. J. Med.264, 953 (1961).

    Article  CAS  PubMed  Google Scholar 

  23. Shirakura, T., M. Azuma and T. Maekawa: Studies on erythropoietic actions of testosterone. Acta haemat.38, 49 (1967).

    Article  CAS  PubMed  Google Scholar 

  24. Steinglass, P., A. S. Gordon and H. A. Charipper: Effect of castration and sex hormones on the blood of rats. Proc. Soc. Exp. Biol. Med.48, 169 (1941).

    Article  CAS  Google Scholar 

  25. Zittoun, R., A. Bernadou, C. M. Blanc, G. Bilski-Pasquier and J. Bousser: La metenolone dans le traitement des insuffisances médullaires. La presse medicale76, 445 (1968).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Neumann, E., Honetz, N. & Wurm, B. Zum Verhalten des Erythropoetins bei aregeneratorischen Blutbildungsstörungen unter Therapie mit anabolen Steroiden. Blut 29, 373–381 (1974). https://doi.org/10.1007/BF01633672

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01633672

Navigation