Zusammenfassung
Die Wirkung der Tranquilizer Haloperidol, Psyquil und Megaphen, der Effekt von Magnesiumchlorid und Prednisolonsuccinat wurden auf die osmotische Hämolyse, die Immunhämolyse und die Agglutinationshemmung getestet. In niedrigen Konzentrationen hatten die Sedativa eine statistisch signifikante Hemmwirkung auf die osmotische Hämolyse. Auf die in vitro-Immunhämolyse und als Agglutinationshemmer wurde keine Effektivität der Tranquilizer festgestellt. Dagegen fand sich für Prednisolonsuccinat eine hochsignifikante Stabilisierung gegen die Immunhämolyse. Durch Tokopherolacetat läßt sich die Immunhämolyse bei Lysolecithineinwirkung hemmen.
Summary
The effect of the tranquilizers Haloperidol, Psyquil and Megaphen, and the effect of Magnesiumchloride and Prednisolonsuccinat were tested on the osmotic hemolysis, the immune hemolysis, and the agglutination inhibition. In low concentration the sedatives had a statistically significant inhibiting effect on the osmotic hemolysis. On the in vitro immune hemolysis and as agglutination inhibitors there was no effectiveness of the tranquilizers determined. On the other hand a highly significant stabilization against the immune hemolysis was found for Prednisolonsuccinat. The immune hemolysis can be inhibited with Tocopherolacetate by use of Lysolecithin.
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Bube, F., Sehrbundt, M. Über die lokale Einwirkung von Sedativa und Prednisolonsuccinat auf die osmotische und die Immun-Hämolyse. Blut 25, 190–202 (1972). https://doi.org/10.1007/BF01632392
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DOI: https://doi.org/10.1007/BF01632392