Abstract
Trabecular volumetric bone mineral density (VMD) was measured at the lumbar spine using quantitative computed tomography (QCT) and at the distal radius using peripheral QCT (pQCT) in 60 Japanese women aged 21–86 years. The age-dependent decrease between age 20 and 80 years was found to be almost identical between vertebral trabecular VMD and radial trabecular VMD, averaging 2.5±0.26 (SE) and 2.5±0.30 mg/cm3 per year, respectively. A highly significant correlation was found between vertebral and radial trabecular VMD (r=0.806,p<0.001) with a prediction error of ±9.6% (± SD/mean). In the present study, a relatively constant trabecular VMD ratio was found between the vertebral and distal radial sites, despite the relatively small study population. This may indicate a close parallelism between vertebral and radial trabecular bone.
Similar content being viewed by others
References
Genant HK, Ettinger B, Harris ST, Block JE, Steiger P. Quantitative computed tomography in assessment of osteoporosis. In: Riggs BL, Melton III LJ, editors. Osteoporosis: etiology, diagnosis, and management. New York: Raven Press, 1988:221–49.
Genant H, Cann CE, Ettinger B, Gordan GS. Quantitative computed tomography of vertebral spongiosa: a sensitive method for detecting early bone loss after oophorectomy. Ann Inter Med 1982;97:699–705.
Fujii Y, Goto B, Miyauchi A, Takagi Y, Fujita T. Fixed ratio between radial cortical volume and density measured by peripheral quantitative computed tomography (pQCT) regardless of age and sex. Calcif Tissue Int 1995;56:586–8.
Genant HK, Cann CE, Pozzi-Mucelli RS, Kanter AS. Vertebral mineral determination by quantitative CT: clinical feasibility and normative data. J Comput Assist Tomogr 1983;7:554.
Fujii Y, Tsutsumi M, Tsunenari T, Fukase M, Fujita T. Quantitative computed tomography of lumbar vertebrae in Japanese patients with osteoporosis. Bone Miner 1989;6:87–94.
Schneider P, Boerner W, Mazess RB, Barden H. The relationship of peripheral to axial bone density. Bone Miner 1988;4:279–87.
Wilson CR. Bone-mineral content of the femoral neck and spine versus the radius and ulna. J Bone Joint Surg Am 1977;59:665–9.
Seeman E, Wahner HW, Offord KP, Kumark R, Johnson WJ, Riggs BL. Differential effects of endocrine dysfunction on the axial and the appendicular skeleton. J Clin Invest 1982;69:1302–9.
Mazess RB, Peppier WW, Chesney RW, Lange TA, Lindgren U, Smith E Jr. Does bone measurement on the radius indicate skeletal status? J Nucl Med 1984;25:281–8.
Hangartner TK, Overton TR, Rigal WM. Comparison of trabecular bone density at axial and peripheral sites using computed tomography. In: Frame B, and Potts J editors. Clinical disorders of bone and mineral metabolism. Amsterdam: Excerpta Medica, 1983:54–7.
Butz S, Wuster C, Scheidt NC, Gotz M, Ziegler R. Forearm BMD as measured by peripheral quantitative computed tomography (pQCT) in a German reference population. Osteoporosis Int 1994;4:179–84.
Grampp S, Lang P, Jergas M, Gluer CC, Engelke K, Steiner E, Genant HK. Assessment of total, trabecular, and cortical bone at radius and spine. J Bone Miner Res 1995;10:(Suppl. 1):M481.
Krinschker U, Bock O. Peripheral and central spongiosa measurements by roentgendensitometry in 150 patients of a clinic for rheumatic diseases. In: Bone morphometry: Sixth international congress, Lexington, USA, 1992.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Fujii, Y., Chikawa, T., Nakamura, T. et al. Comparison of trabecular bone density at vertebral and radial sites using quantitative computed tomography. Osteoporosis Int 6, 486–490 (1996). https://doi.org/10.1007/BF01629582
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01629582