Skip to main content
Log in

Diabetic fibrous mastopathy

Report of two cases

  • Case Report
  • Published:
Virchows Archiv A Aims and scope Submit manuscript

Summary

Two cases of a characteristic form of fibrous mastopathy associated with type I diabetes mellitus are described. Well-circumscribed nests of mature lymphocytes in a hyaline stroma are the hallmark of this condition. In one case mastectomy was performed, as the lesion had been interpreted as malignant on frozen section. It appears that this form of “idiopathic mastopathy” deserves wider recognition.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Azzopardi JG (1979) Major problems in breast pathology. Saunders, Philadelphia

    Google Scholar 

  • Byrd BF Jr, Hartmann WH, Graham LS, Hogle HH (1987) Mastopathy in insulin-dependent diabetics. Ann Surg 205:529–532

    Google Scholar 

  • Clement P, Senges H, How AS (1987) Giant cell arteritis of the breast: case report and review of the literature. Hum Pathol 18:1186–1189

    Google Scholar 

  • Fletcher A, Magrath IM, Riddell RH, Talbot IC (1982) Granulomatous lobular mastitis: a report of seven cases. J Clin Pathol 35:941–945

    Google Scholar 

  • Hsu SM, Raine L, Fanger H (1981a) A comparative study of the peroxidase-antiperoxidase method and an avidin-biotin-complex method for studying polypeptide hormones with radioimmunoassay antibodies. Am J Clin Pathol 75:734–738

    Google Scholar 

  • Hsu SM, Raine L, Fanger H (1981b) Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabelled (PAP) procedures. J Histochem Cytochem 29:577–580

    Google Scholar 

  • Kessler E, Wooloch Y (1972) Granulomatous mastitis: a lesion clinically simulating carcinoma. Am J Clin Pathol 58:642–646

    Google Scholar 

  • Lamovec J, Jancar J (1987) Primary malignant lymphoma of the breast. Cancer 60:3033–3041

    Google Scholar 

  • Lin JJ, Farha GJ, Taylor RJ (1980) Pseudolymphoma of the breast. Cancer 45:973–978

    Google Scholar 

  • Page DL, Anderson TJ (1987) Diagnostic histopathology of the breast. Churchill Livingstone, Edinburgh

    Google Scholar 

  • Rosai J (1988) Ackerman's surgical pathology. Mosby, St. Louis

    Google Scholar 

  • Soler NG, Khardori R (1984) Fibrous disease of the breast, thyroiditis, and cheiroarthropathy in type I diabetes mellitus. Lancet I:193–194

    Google Scholar 

  • Tomaszewski JE, Brooks JJ, Hicks D, Livolsi VA (1990) Diabetic mastopathy: an autoimmune mastitis? (abstract). United States and Canadian Academy of Pathology, Annual Meeting. Lab Invest 62:587:100A

    Google Scholar 

  • Underwood JCE, Parsons MA, Harris SC, Dundas SAC (1988) Frozen sections appearances simulating invasive lobular carcinoma in breast tissue adjacent to inflammatory lesions and biopsy sites. Histopathology 13:232–234

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Foschini, M.P., Cavazza, A., Macedo Pinto, I.M. et al. Diabetic fibrous mastopathy. Vichows Archiv A Pathol Anat 417, 529–532 (1990). https://doi.org/10.1007/BF01625734

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01625734

Key words

Navigation