Skip to main content
SpringerLink
Log in

Detection of 4-hydroxy-BHT residues in laboratory animals as an indicator of exposure to butylated hydroxytoluene (BHT)

  • Published:
Bulletin of Environmental Contamination and Toxicology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Collings AJ, Sharratt M (1970) The BHT content of human adipose tissue. Food Cosmet Toxicol 8:409–412

    Google Scholar 

  • Daniel JW, Gage JC (1965) The absorption and excretion of butylated hydroxytoluene (BHT) in the rat. Food Cosmet Toxicol 3:405–415

    Google Scholar 

  • Gilbert D, Golberg L (1965) Liver response tests. III. Liver enlargement and stimulation of microsomal processing enzyme activity. Food Cosmet Toxicol 3:417–432

    Google Scholar 

  • Gudzinowicz BJ (1967) Gas Chromatographic analysis of drugs and pesticides. M. Dekker, New York, pp. 512–537

    Google Scholar 

  • Kharasch MS, Joshi BS (1957) Reactions of hindered phenols. II. Base-catalyzed oxidations of hindered phenols. J Org Chem 22:1439–1443

    Google Scholar 

  • Mizutani T, Ohe T (1976) Hygienic chemical studies on 3,5-di-tert-butyl-4-hydroxytoluene (BHT). II. Determination of 3,5-di-tert-butyl-4-hydroxytoluene (BHT) in human adipose tissue. Eisei Kagaku 22:265–270

    Google Scholar 

  • Mizutani T, Yamamoto K, Tajima K (1983) Isotope effects on the metabolism and pulmonary toxicity of butylated hydroxytoluene in mice by deuteration of the 4-methyl group. Toxicol Appl Pharmacol 69:283–290

    Google Scholar 

  • Shaw Y-S, Chen C (1972) Ring hydroxylation of di-t-butylhydroxytoluene by rat liver microsomal preparations. Biochem J 128:1285–1291

    Google Scholar 

  • Yamamoto K, Tajima K, Mizutani T (1979) Identification of new metabolites of butylated hydroxytoluene (BHT) in rats. J Pharm Dyn 2:164–168

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. School of Pharmacy, Hokuriku University, 920-11, Kanazawa, Japan

    Kenji Yamamoto & Kazuo Tajima

  2. Faculty of Living Science, Kyoto Prefectural University, 606, Kyoto, Japan

    Tamio Mizutani

Authors
  1. Kenji Yamamoto
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Kazuo Tajima
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Tamio Mizutani
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Yamamoto, K., Tajima, K. & Mizutani, T. Detection of 4-hydroxy-BHT residues in laboratory animals as an indicator of exposure to butylated hydroxytoluene (BHT). Bull. Environ. Contam. Toxicol. 33, 533–537 (1984). https://doi.org/10.1007/BF01625580

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01625580

Keywords

Search

Navigation