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Bone mass measurement for premenopausal women

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Abstract

Bone mass measurement is a useful tool in determining the risk of fracture. However, there are questions about whether or not bone mass measurement should be used in premenopausal women. Part of the problem concerns the issue of whether or not bone mass or bone density falls prior to menopause. Significant prospective data are still being gathered on this issue, which is hotly debated. In addition, even if there is a loss of bone density prior to menopause, it is not evident what clinical strategy would result from the measurement. At present, therefore, it seems prudent only to measure bone mass of women who have significantly impaired ovarian function or who are approaching menopause.

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References

  1. Hui SL, Slemenda SW, Johnston CC Jr. Baseline measurement of bone mass predicts fracture in white women. Ann Intern Med 1989;111:355–61.

    Google Scholar 

  2. Cummings SR, Black DM, Nevitt MC, et al. Bone density at various sites for prediction of hip fractures. Lancet 1993;341:72–5.

    Google Scholar 

  3. Johnston CC, Melton LJ III, Lindsay R, et al. Clinical indications for bone mass measurement. J Bone Miner Res 1989;(Suppl 2):1–28.

    Google Scholar 

  4. Diagnostic and Therapeutic Assessment (DATTA). Measurement of bone density with dual x-ray absorptiometry (DEXA). J Am Med Assoc 1992;267:286–94.

    Google Scholar 

  5. Cann CE, Genant HK, Kolb FO, et al. Quantitative computed tomography for prediction of vertebral fracture risk. Bone 1985;6:1–7.

    Google Scholar 

  6. Baran DT. The magnitude and determinant of premenopausal bone loss. Osteoporosis Int 1994;4 (Suppl 1):S31–4

    Google Scholar 

  7. Riis B. Premenopausal bone loss: fact or artifact? Osteoporosis Int 1994;4 (Suppl 1):S35–7.

    Google Scholar 

  8. Lindsay R, Cosman F, Herrington BS, Himmestein S. Bone mass and body composition in normal women. J Bone Miner Res 1992;7:55–63.

    Google Scholar 

  9. Stevenson JC, Lees B, Devenport M, et al. Determinants of bone density in normal women: risk factors for future osteoporosis? BMJ 1989;298:924–8.

    Google Scholar 

  10. Warren MP. Amenorrhea in endurance runners. J Clin Endocrinol Metab 1992;75:1393–7.

    Google Scholar 

  11. Slemenda CW, Johnston CC. High intensity activities in young women: site specific bone mass effects among female figure skaters. Bone Miner 1993;20:125–32.

    Google Scholar 

  12. Hetland ML, Haarbo J, Christiansen C, Larsen T. Many runners have menstrual dysfunction, but bone density if only affected in amenorrheoeics [abstract]. Presented at Fourth International Symposium on Osteoporosis, Hong Kong, 1993:158.

  13. Seeman E, Szmukler CI, Formica C, Tsalamaneris C, Mestrovic R. Osteoporosis in anorexia nervosa: the influence of peak bone density, bone loss, oral contraceptive use, and exercise. J Bone Miner Res 1992;7:1467–74.

    Google Scholar 

  14. Kiriike N, Iketani T, Nakanishi S, Nagata T, Inoue K, Okuna M, et al. Reduced bone density and major hormones regulating calcium metabolism in anorexia nervosa. Acta Psychiatr Scand 1992;86:358–63.

    Google Scholar 

  15. Rico H, Arnanz F, Revilla M, Perera S, Iritia M, Villa LF, Arribas L. Total and regional bone mineral content in women treated with GnRH agonist. Calcif Tissue Int 1993;52:354–7.

    Google Scholar 

  16. Mueller M, Jurist TM. Skeletal status in rheumatoid arthritis: a preliminary report. Arth Rheum 1973;16:66–70.

    Google Scholar 

  17. Cosman F, Nieves J, Gordon S, Shen V, Herbert J, Lindsay R. High dose IV steroids acutely depress serum phosporus and elevate 1,25(OH)2D prior to an increase in PTH. J Bone Miner Res 1992;7 (Suppl 1);S168.

  18. Lindsay R. Prevention and treatment of osteoporosis. Lancet 1993;341:801–5.

    Google Scholar 

  19. Prior JC, Vigna YM, Schechter MT, et al. Spinal bone loss and ovulatory disturbances. N Engl J Med 1992;323:1221–7.

    Google Scholar 

  20. Myburgh KH, Hutchins J, Fataar AB, Hough SF, Noakes TD. Low bone density is an etiologic factor for stress fractures in athletes. Ann Intern Med 1990;113:754–9.

    Google Scholar 

  21. Pouilles JM, Tremollieres F, Ribot C. The effect of menopause on longitudinal bone loss from the spine. Calcif Tissue Int 1993;52:340–3.

    Google Scholar 

  22. Lindsay R, Hart DM, Forrest C, et al. Prevention of spinal osteoporosis in oophorectomized women. Lancet 1980;2:1151–4.

    Google Scholar 

  23. Naessen T, Persson I, Ljunghall S, Bergstrom R. Women with climacteric symptoms: a target group for prevention of rapid bone loss and osteoporosis. Osteoporosis Int 1992;2:225–31.

    Google Scholar 

  24. Ryan PJ, Harison R, Blake GM, Fogelman I. Compliance with hormone replacement therapy (HRT) after screening for postmenopausal osteoporosis. Br Obstet Gynaecol 1992;99:325–8.

    Google Scholar 

  25. Siebel MJ, Cosman F, Shen V, Gordon S, Dempster DW, Ratcliffe A, Lindsay R. Urinary hydroxypyridinium crosslinks of collagen as markers if bone resorption and estrogen efficacy in postmenopausal osteoporosis. J Bone Miner Res 1993;8:881–9.

    Google Scholar 

  26. Delmas PD. Biochemical markers of bone turnover for clinical investigation ofosteoporosis. Osteoporosis Int 1993;3 (Suppl 1): S81–6.

    Google Scholar 

  27. Eyre D. Biomarkers of bone resorption [Editorial]. J Clin Endocrinol Metab 1993;74:470.

    Google Scholar 

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Authors and Affiliations

  1. Helen Hayes Hospital, West Haverstraw, and Columbia University College of Physicians and Surgeons, New York, New York, USA

    R. Lindsay MBChB, PhD (FRCP, Chief)

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  1. R. Lindsay MBChB, PhD
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Lindsay, R. Bone mass measurement for premenopausal women. Osteoporosis Int 4 (Suppl 1), S39–S41 (1994). https://doi.org/10.1007/BF01623434

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  • DOI: https://doi.org/10.1007/BF01623434

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