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Screening for osteoporosis: Comparison between dual energy X-ray absorptiometry and broadband ultrasound attenuation in 1000 perimenopausal women

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Abstract

This paper compares dual-energy X-ray absorptiometry (DXA) of the spine and hip and broadband ultrasound attenuation (BUA) of the os calcis in 1000 perimenopausal women aged between 45 and 49 years who attended a randomized Osteoporosis Screening Programme. Significant correlations were found between all DXA results and BUA, with the trochanter giving the best numerical correlation with BUA (r=0.354,p<0.0001). BUA was not successful in predicting women with low DXA measurements, with only 44.0% of the women whose spinal DXA falls within the lowest quartile being in the lowest quartile of BUA. Although BUA is a poor predictor of spinal and hip bone mineral density it may provide additional structural information important in fracture prediction.

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References

  1. Wasnich RD, Ross PD, Heilburn LK, Vogel JM. Selection of optimal skeletal site for fracture risk prediction. Clin Orthop Rel Res 1987;216:262–8.

    Google Scholar 

  2. Cummings SR, Black DM, Nevitt MC, et al. Appendicular bone density and age predicts hip fracture in women. JAMA 1990;263:665–8.

    Google Scholar 

  3. Langton CM, Palmer SB, Porter RW. The measurement of Broadband ultrasound attenuation in cancellous bone. Eng Med 1984; 13:89–91.

    Google Scholar 

  4. Editorial. Ultrasound and bone fragility. Lancet 1989;4:842.

  5. Porter RW, Miller CG, Grainger D, Palmer SB. Prediction of hip fracture in elderly women: a prospective study. BMJ 1990;301:638–41.

    Google Scholar 

  6. Heaney RP, Avioli LV, Chestnut CH, et al. Osteoporotic bone fragility: detection by ultrasound transmission velocity. JAMA 1989;261:2986–90.

    Google Scholar 

  7. Camporeale A, Cepollaro C, Zacchei F, et al. Ultrasound transmission velocity in normal and osteoporotic postmenopausal women. In: Christiansen C, Overgaard K, editors. Osteoporosis 2. Copenhagen: Osteopress ApS, 1990:670–2.

    Google Scholar 

  8. Rossman P, Zagzebski J, Mesina C, Sorenson J, Mazees R. Comparison of speed of sound and ultrasound attenuation in the os calcis to bone density of the radius, femur and lumbar spine. Clin Phys Physiol Meas 1989; 10:353–60.

    Google Scholar 

  9. Mazees R, Collick B, Trempe J, Barden H, Hanson J. Performance evaluation of a dual energy X-ray bone densitometer. Calcif Tissue Int 1989;44:228–42.

    Google Scholar 

  10. Need AG, Nordin BEG, Horowitz M, Morris HA. Osteoporosis: new insights from bone densitometry. J Am Geriatr Soc 1990;38:1153–8.

    Google Scholar 

  11. Vogel JM, Wasnich RD, Ross PD. Clinical relevance of calcaneus bone mineral measurement: a review. Bone Miner 1988;5:35–58.

    Google Scholar 

  12. Baran DT, Kelly AM, Karellas A, et al. Ultrasound attenuation of the os calcis in women with osteoporosis and hip fractures. Calcif Tissue Int 1988;43:138–42.

    Google Scholar 

  13. Gardsell P, Johnell O, Nilsson BE. Predicting fractures in women by using forearm bone densitometry. Calcif Tissue Int 1989;44:235–42.

    Google Scholar 

  14. Ross PD, Davis JW, Epstein RS, Wasnich RD. Pre-existing fractures and bone mass predict vertebral fracture incidence in women. Ann Intern Med 1991;114:919–23.

    Google Scholar 

  15. McCloskey EV, Murray SA, Miller C, et al. Broadband ultrasound attenuation in the os calcis: relationships to bone mineral at other skeletal sites. Clin Sci 1990;78:227–33.

    Google Scholar 

  16. Resch H, Pietschmann P, Bernecker P, Krexner E, Wilvonseder R. BUA: a new diagnostic method in osteoporosis. AJR 1990;155:825–8.

    Google Scholar 

  17. Porter RW, Johnson K, McCutcheon JDS. Wrist fracture, heel bone density and thoracic kyphosis: a case control study. Bone 1990;11:211–4.

    Google Scholar 

  18. Agren M, Karellas A, Leahey D, Marks S, Baran D. Ultrasound attenuation of the calcaneus: a sensitive and specific discriminator of osteopenia in postmenopausal women. Calcif Tissue Int 1989;44:228–32.

    Google Scholar 

  19. Hosie CJ, Smith DA, Deacon AD, Langton CM. Comparison of broadband ultrasound attenuation of the os calcis and quantitative computed tomography of the distal radius. Clin Phys Physiol Meas 1987;8:303–8.

    Google Scholar 

  20. Parfitt AM, Mathews CHE, Villanueva AR, Kleerekoper M, Frame B, Rao DS. Relationships between surface, volume and thickness of iliac trabecular bone in ageing and in osteoporosis. J Clin Invest 1983;72:1396–409.

    Google Scholar 

  21. Parfitt AM. Trabecular bone architecture in pathogenesis and prevention of fracture. Am J Med 1987;82[Suppl 1b]:68–72.

    Google Scholar 

  22. Recker RR. Low bone mass may not be the only cause of skeletal fragility in osteoporosis. Proc Soc Biol Med 1989;191:272–4.

    Google Scholar 

  23. Gluer CC. Broadband ultrasound attenuation of the heel versus single photon absorptiometry of the heel: Do these techniques measure different entities? J Bone Miner Res 1991;6 suppl:169.

    Google Scholar 

  24. Langton CM, Evans GP, Hodgskinson R, Riggs CM. Ultrasonic, elastic and structural properties of cancellous bone. In: Current research in osteoporosis and bone mineral measurement. Bath: BIR, 1990:10–11.

    Google Scholar 

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Massie, A., Reid, D.M. & Porter, R.W. Screening for osteoporosis: Comparison between dual energy X-ray absorptiometry and broadband ultrasound attenuation in 1000 perimenopausal women. Osteoporosis Int 3, 107–110 (1993). https://doi.org/10.1007/BF01623382

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  • DOI: https://doi.org/10.1007/BF01623382

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