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Starch-gel electrophoresis of liver esterases selectively inhibited by pesticides

Conclusion

The studies presented here indicate that selective inhibition of liver esterases or bands by pesticides can be evaluated rapidly by starch-gel electrophoresis. The liver esterase inhibition — starch-gel electrophoretic procedure described may be useful in screening pesticides with selective or specific toxicity to a particular species. A similar method has already been used to demonstrate the relation of esterase inhibition with acute organophosphorus poisoning in pheasants (14). The ability of Dyrene heated in methanol to strongly inhibit liver esterases is noteworthy and will be reported elsewhere.

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References

  1. 1.

    ACKERMAN, H. J. Chromatog. 36, 309 (1968).

    Google Scholar 

  2. 2.

    BUNYAN, P.J., Analyst 89, 615 (1964).

    Google Scholar 

  3. 3.

    FALLSCHEER, H.O., and COOK, J.W. J. Assoc. Offic. Agric. Chem. 39, 691 (1956).

    Google Scholar 

  4. 4.

    MCKINLEY, W.P., and JOHAL, P.S. J. Assoc. Offic. Agric. Chem. 46, 840 (1963).

    Google Scholar 

  5. 5.

    MCKINLEY, W.P., and READ, S.I. J. Assoc. Offic. Agric. Chem. 44, 726 (1961).

    Google Scholar 

  6. 6.

    MENDOZA, C.E., GRANT, D.L., BRACELAND, B., and MCCULLY, K.A. Analyst 94, 805 (1969).

    Google Scholar 

  7. 7.

    MENDOZA, C.E., WALES, P.J., MCLEOD, H.A., and MCKINLEY, W.P. Analyst 93, 34 (1968).

    Google Scholar 

  8. 8.

    MENDOZA, C.E., WALES, P.J., MCLEOD, H.A., and MCKINLEY, W.P. Analyst 93, 173 (1968).

    Google Scholar 

  9. 9.

    WALES, P.J., MCLEOD, H.A., and MCKINLEY, W.P. J. Assoc. Offic. Anal. Chem. 51, 1239 (1968).

    Google Scholar 

  10. 10.

    WINTERLIN, W., WALKER, G., and FRANK, H. J. Agr. Food Chem. 16, 808 (1968).

    Google Scholar 

  11. 11.

    SMITHIES, O. Biochem. J. 61, 629 (1955).

    Google Scholar 

  12. 12.

    UICHIDA, T., DAUTERMAN, W.C., O'BRIEN, R.D. J. Agr. Food Chem. 12, 48 (1964).

    Google Scholar 

  13. 13.

    BUNYAN, P.J., JENNINGS, D.M., and TAYLOR, A. J. Agr. Food Chem. 16, 332 (1968).

    Google Scholar 

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Mendoza, C.E., Hatina, G.V. Starch-gel electrophoresis of liver esterases selectively inhibited by pesticides. Bull. Environ. Contam. Toxicol. 5, 181–190 (1970). https://doi.org/10.1007/BF01617197

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Keywords

  • Methanol
  • Toxicity
  • Waste Water
  • Electrophoresis
  • Water Management