Skip to main content
Log in

Effect of some anionic surfactants on the stability of oxytetracycline hydrochloride stabilized emulsion

  • Original Contributions
  • Colloid Science
  • Published:
Colloid and Polymer Science Aims and scope Submit manuscript

Summary

The zeta potential of oxytetracycline hydrochloride stabilized emulsion flocculated by the addition of anionic surfactants has been calculated. The interaction energies of these emulsions have also been evaluated and the stability discussed in the light of D. L. V. O. Theory. The energy barriers, thus obtained, were very high, which prevented the occurrence of flocculation in primary minima. The flocculation could, however, occur in the secondary minima. The flocculation studies were carried out haemocytometrically and the degree of aggregation (D) calculated. In order to account for the observed values ofD, the effective Van der Waals constant of the system should be 2.3 x 10-13 erg. The binding parameters and free energy of adsorption have also been calculated.

Zusammenfassung

In der Arbeitr wird über die Berechnung des Zetapotentials von Emulsionen berichtet, die mit Oxytetracyclinhydrochlorid stabilisiert und durch Zusatz von anionischen Tensiden geflockt wurden. Auch die Wechselwirkungsenergien werden abgeschätzt und die Stabilität im Licht der DLVO-Theorie diskutiert. Die so erhaltenen Energiebarrieren sind sehr hoch und verhindern eine Flockung im primären Minimum. Die Flockung könnte jedoch im sekundären Minimum erfolgen. Die Untersuchungen wurden durch Flockungsstudien ergänzt, ebenso durch Berechnung von Bindungsparametern und der freien Energie der Adsorption.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Cockbain, E. G., Trans. Faraday Soc.48, 185 (1952).

    Google Scholar 

  2. Higuchi, W. I., R. Okada, andA. P. Lemberger, J. Pharm. Sci.51, 683 (1962).

    Google Scholar 

  3. Verwey, E. W. andT. C. Overbeek, Theory of Stability of Lyophobic Colloids (Amsterdam 1948).

  4. Derjaguin, B. andM. Kussakov, Acta Phys. Chem. URSS10, 25 and 153 (1939).

    Google Scholar 

  5. Schenkel, J. N. andJ. A. Kitcbener, Trans. Faraday Soc.56, 161, (1960).

    Google Scholar 

  6. Prakash, C. andS. N. Srivastava, Bull Chem. Soc., Japan40, 1765 (1967).

    Google Scholar 

  7. Hemaker, H. C., Physics4, 1058 (1937).

    Google Scholar 

  8. Slater, J. C. andJ. G. Kirkwood, Phys. Rev.37, 682 (1931).

    Google Scholar 

  9. Maelulyn Huges, E. A., Physical Chem. (Pergamdi Press, London) 383 (1965).

  10. Neugebaur, T., Z. Phys.107, 785 (1937).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

With 6 figures and 4 tables

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sbarma, M.K., Srivastava, S.N. Effect of some anionic surfactants on the stability of oxytetracycline hydrochloride stabilized emulsion. Colloid & Polymer Sci 255, 887–895 (1977). https://doi.org/10.1007/BF01617096

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01617096

Keywords

Navigation