Summary
It was shown in the present study that irradiation of a multiclonal tumor may destroy near-diploid cell clones preferentially, while the stemline with high DNA content continues to grow after temporary arrest. This experimental observation confirms recent clinical studies.
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Wagner, W. DNA index — parameter for the prediction of prognosis and primary radioresistance?. J Cancer Res Clin Oncol 116, 315–317 (1990). https://doi.org/10.1007/BF01612911
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DOI: https://doi.org/10.1007/BF01612911