Abstract
We use the subset containment relation to construct a probabilistic nonadaptive group testing design and decoding algorithm that, in the presence of testing errors, identifies many positives in a population. We give a lower bound for the expected portion of positives identified as a function of an upper bound on the number of testing errors.
Similar content being viewed by others
References
D.J. Balding and D.C. Torney, Optimal pooling designs with error detection, J. Combin. Theory, Ser. A74 (1996).
D.J. Balding et al., A comparative survey of non-adaptive pooling designs, In: Genetic Mapping and DNA Sequencing, IMA Volumes in Mathematics and its Applications, Springer Verlag, 1995, pp. 133–155.
W.J. Bruno et al., Design of efficient pooling experiments, Genomics26 (1995) 21–30.
R. Dorfman, The detection of defective members of a large population, Ann. Math. Stat.14 (1943) 436–440.
D-Z. Du and F.K. Hwang, Combinatorial Group Testing and Its Applications, World Scientific, Singapore, 1993.
A. D'yachkov, A. Macula, and V. Rykov, On optimal parameters of a class of superimposed codes and designs, submitted, 1997.
A. D'yachkov and V. Rykov, Superimposed distance codes, Problems Contr. and Inf. Theory18 (1989) 237–250.
Farach et al., Group testing problems with sequences experimental molecular biology, In: Proceedings of Compression and Complexity of Sequences, 1997, B. Carpentieri et al., Eds., IEEE Press, 1994, pp. 357–367.
E. Knill, Lower bounds for identifying subset members with subset queries, In: Proceedings of the Sixth Annual ACM-SIAM Symposium on Discrete Algorithms, Association for Computing Machinery and Society for Industrial and Applied Mathematics, 1995, pp. 369–377.
E. Knill et al., Non-adaptive group testing in the presence of errors, Discrete Appl. Math.88 (1998) 261–290.
A. Macula, A simple construction of d-disjunct matrices with certain constant weights, Discrete Math.162 (1996) 311–312.
A. Macula, Nonadaptive group testing with error-correctingd e-disjunct matrices, Discrete Appl. Math.80 (1997) 217–282.
A. Macula, Probabilistic nonadaptive and two-stage group testing with relatively small pools and DNA library screening, J. Combin. Optimization, to appear.
Author information
Authors and Affiliations
Additional information
The algorithms contained herein are part of The State University of New York Research Foundation invention C1230-125, Probabilistic and Combinatorial Nonadaptive and Two-Stage Group Testing and DNA Library Screening by A. Macula and K. Anne.
Rights and permissions
About this article
Cite this article
Macula, A.J. Probabilistic nonadaptive group testing in the presence of errors and DNA library screening. Annals of Combinatorics 3, 61–69 (1999). https://doi.org/10.1007/BF01609876
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF01609876