Skip to main content
SpringerLink
Log in

Influence of herpes simplex virus infection on benzo(a)pyrene metabolism in monkey kidney cells

  • Published:
Bulletin of Environmental Contamination and Toxicology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Buening MK, Wislocki PG, Levin W, Yagi H, Thakker DR, Akagi H, Koreeda M, Jerina DM, Conney AH (1978) Tumorigenicity of the optical enantiomers of the diastereomeric benzo(a)pyrene 7,8-diol-9,10-epoxides in newborn mice. Proc Natl Acad Sci USA 75:5358–5361

    Google Scholar 

  • Casto B, Pieczynski WJ, DiPaolo JA (1974) Enhancement of adenovirus transformation by treatment of hamster embryo cells with diverse chemical carcinogens. Cancer Res 34:72–78

    Google Scholar 

  • Cohen GM, McLeod MC, Moore CJ, Selkirk JK (1980) Metabolism and macromolecular binding of carcinogenic and noncarcinogenic metabolites of benzo(a)-pyrene by hamster embryo cells. Cancer Res 40:207–211

    Google Scholar 

  • Diamond L, (1971) Metabolism of polycyclic hydrocarbons in mammalian cell cultures. Int J Cancer 8:451–469

    Google Scholar 

  • DiPaolo JA, Casto BC (1978)In Vitro transformation of mammalian cells: Sequential treatment with diverse agents. In: Slaga TJ, Sivak A, Boutwell RK, (eds) Carcinogensis, Vol 1 Raven Press, New York, p 517

    Google Scholar 

  • Duff R, Rapp F (1971) Properties of hamster embryo fibroblasts transformedin vitro after exposure to ultraviolet-irradiated herpes simplex virus type 2. J Virol 8:469–477

    Google Scholar 

  • Dunn BP, Fee J (1979) Polycyclic aromatic hydrocarbons in commercial seafoods. J Fish Res Board Can 36:1469–1476

    Google Scholar 

  • Hall MR, Stoming TA (1980) Benzo(a)pyrene metabolism in cells productively infected with simian virus 40. Chem-Biol Interactions 32:111–123

    Google Scholar 

  • Howard JW, Fazio T (1980) Review of polycyclic aromatic hydrocarbons in foods. J Assoc Off Anal Chem 63:1077–1104

    Google Scholar 

  • Iosifidou H, Kilikidis SD, Kamarianos A (1982) Analysis for polycyclic aromatic hydrocarbons in mussels from the Thermaikos gulf, Greece. Bull Environ Contam Toxicol 28:535–541

    Google Scholar 

  • Howett MK, Pegg AE, Rapp F (1979) Enhancement of biochemical transformation of mammalian cells by herpes simplex virus following nitrosomethylurea treatment. Cancer Res 39:1041–1045

    Google Scholar 

  • Koreeda M, Moore PD, Wislocki PG, Levin W, Conney H, Yagi H, Jerina DM (1978) Binding of benzo(a)pyrene 7,8-diol-9,10-epoxides to DNA, RNA, and protein of mouse skin occurs with high stereoselectivity. Science 199:778–781

    Google Scholar 

  • Levin W (1978) Polycyclic hydrocarbons and cancer. In: Gelboin HV, Tso POP (eds) Environmental chemistry and metabolism, Vol 1 Academic Press, New York, P 189

    Google Scholar 

  • Murakami M, Fukami J-I (1980) Incorporation of labeled pesticides and environmental chemicals into nuclear fraction of cultured human cells. Bull Environ Contam Toxicol 24:27–30

    Google Scholar 

  • National Academy Of Sciences (1972) Particulate polycyclic organic material. Printing and Publishing Office. National Academy of Sciences, Washington, D.C.

    Google Scholar 

  • Nebert DW, Gelboin HV (1968) Substrate-inducible microsomal aryl hydroxylase in mammalian cells. J Biol Chem 243:6242–6249

    Google Scholar 

  • Obana H, Hori S, Kashimoto T, Kunita N (1981) Polycyclic aromatic hydrocarbons in human fat and liver. Bull Environ Contam Toxicol 27:23–27

    Google Scholar 

  • Pearson GR, Beneke JS (1977) Inhibition of herpesvirus saimiri replication by phosphonoacetic acid, benzo(a)pyrene, and methylcholanthrene. Cancer Res 37:42–50

    Google Scholar 

  • Selkirk JK, Croy RG, Gelboin, HV (1974) Benzo(a)-pyrene metabolites: efficient and rapid separation by high-pressure liquid chromatography. Science 184:169–171

    Google Scholar 

  • Skare J, Summers WP, Summers WC (1975) Structure and function of herpesvirus genomes. J Virol 15:726–732

    Google Scholar 

  • Sydiskis RJ, Roizman B (1967) The disaggregation of host polyribosomes in productive and abortive infection with herpes simplex virus. Virol 32:678–686

    Google Scholar 

  • Thakker DR, Yagi H, Lu, AYH, Levin W, Conney AH, Jerina DM (1976) Metabolism of benzo(a)pyrene: conversion of (±)-trans-7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene to highly mutagenic 7,8-diol-9,10-epoxides. Proc Natl Acad Sci USA 73:3381–3385

    Google Scholar 

  • Tomingas R, Pott F, Dehnen W (1976) Polycyclic aromatic hydrocarbons in human bronchial carcinoma. Cancer Letters 1:189–195

    Google Scholar 

  • Weinstein IB, Jeffrey AM, Jennette KW, Blobstein SH, Harvey RG, Harris C, Autrup H, Kasai H, Nakanishi K (1976) Benzo(a)pyrene diol epoxides as intermediates in nucleic acid binding in Vitro and inVivo. Science 193:592–595

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Departments of Biochemistry, University of Nevada, 89557, Reno, NV

    John H. Degenhardt

  2. Departments of Microbiology, School of Medicine, University of Nevada, 89557, Reno, NV

    Mark R. Hall

  3. Atmospheric Sciences Center, Desert Research Institute, 89506, Reno, NV

    Bruce Whitcomb

Authors
  1. John H. Degenhardt
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Bruce Whitcomb
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Mark R. Hall
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Degenhardt, J.H., Whitcomb, B. & Hall, M.R. Influence of herpes simplex virus infection on benzo(a)pyrene metabolism in monkey kidney cells. Bull. Environ. Contam. Toxicol. 32, 1–9 (1984). https://doi.org/10.1007/BF01607458

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01607458

Keywords

Search

Navigation