Summary
We report the first case of an intravascular glomus tumour, which was located in the right forearm of a 40-year-old male. Microscopically the lesion originated from the wall of a vein and protruded into the lumen of the affected blood vessel. The tumour cells were characterized immunohistochemically by the presence of vimentin, actin and myosin. Within the tumour, small nerves, immunopositive for S-100 protein and neurofilaments, could be identified. Histogenetically, the tumour is thought to derive from intramural epithelioid cells of the venous part of an arteriovenous anastomosis.
Similar content being viewed by others
References
Aiba M, Hirayama A, Kuramochi S (1988) Glomangiosarcoma in a glomus tumor. An immunohistochemical and ultrastructural study. Cancer 61:1467–1471
Anagnostou GD, Papademetriou DG, Toumazani MN (1973) Subcutaneous glomus tumors. Surg Gynecol Obstet 136:945–950
Cordell JL, Falini B, Erber WN, Ghosh AK, Abdulaziz Z, MacDonald S, Pulford KAF, Stein H, Mason DY (1984) Immunoenzymatic labelling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes). J Histochem Cytochem 32:219–229
Dervan PA, Tobbia IN, Casey M, O'Loughlin J, O'Brien M (1989) Glomus tumours: an immunohistochemical profile of 11 cases. Histopathology 14:483–491
Enzinger FM, Weiss SW (1988) Soft tissue tumors, 2nd edn. Mosby, St. Louis, pp 581–595
Kanwar YS, Manaligod JR (1975) Glomus tumor of the stomach. Arch Pathol 99:392–397
Miettinen M (1988) Antibody specific to muscle actins in the diagnosis of soft tissue tumors. Am J Pathol 130:205–215
Miettinen M, Lehto VP, Virtanen I (1983) Glomus tumor cells: evaluation of smooth muscle and endothelial cell properties. Virchows Arch [B] 43:139–149
Mullis WF, Rosato FE, Rosato EF, Butler CJ, Mayer LJ (1972) The glomus tumor. Surg Gynecol Obstet 135:705–707
Popoff NW (1934) The digital vascular system with reference to the state of the glomus in inflammation, arteriosclerotic gangrene, diabetic gangrene, thrombangitis obliterans and supernumerary digits in man. Arch Pathol 18:295–330
Slater DN, Cotton DWK, Azzopardi JG (1987) Oncocytic glomus tumour: a new variant. Histopathology 11:523–531
Sunderraj S, Al-Khalifa AA, Pal AK, Pim HP, Sabri SH (1989) Primary intra-osseous glomus tumour. Histopathology 14:532–536
Tsuneyoshi M, Enjoji M (1982) Glomus tumor. A clinicopathologic and electron microscopic study. Cancer 50:1601–1607
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Beham, A., Fletcher, C.D.M. Intravascular glomus tumour: a previously undescribed phenomenon. Vichows Archiv A Pathol Anat 418, 175–177 (1991). https://doi.org/10.1007/BF01600294
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01600294